Women's Hormone Test Panel — Basic

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: DHEA Dehydroepiandrosterone Unconjugated LCMSMS

DHEA, LC/MS/MS

DHEA-sulfate test measures the amount of DHEA-sulfate in the blood. DHEA-sulfate is a weak male hormone (androgen) produced by the adrenal gland in both men and women. This test is done to check the function of the adrenal glands. The adrenal gland is one of the major sources of androgens in women. The DHEA-sulfate test is often done in women who have male body characteristics (virilism) or excessive hair growth (hirsutism). It is also done in children who are maturing too early (precocious puberty).

Estradiol

Estradiol (estradiol-17 beta, E2) is part of an estrogen that is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. Estradiol (E2) is the predominant form of estrogen and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. Estradiol levels are used in evaluating ovarian function. Estradiol levels are increased in cases of early (precocious) puberty in girls and gynecomastia in men. Its main use has been in the differential diagnosis of amenorrhea – for example, to determine whether the cause is menopause, pregnancy, or a medical problem. In assisted reproductive technology (ART), serial measurements are used to monitor follicle development in the ovary in the days prior to in vitro fertilization. Estradiol is also sometimes used to monitor menopausal hormone replacement therapy.

Also known as: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH), Follicle Stimulating Hormone and Luteinizing Hormone

Fsh

Lh

Also known as: PRL

Prolactin

Prolactin is a hormone produced by the anterior portion of the pituitary gland, a grape-sized organ found at the base of the brain. Prolactin secretion is regulated and inhibited by the brain chemical dopamine. Normally present in low amounts in men and non-pregnant women, prolactin's primary role is to promote lactation (breast milk production). Prolactin levels are usually high throughout pregnancy and just after childbirth. During pregnancy, the hormones prolactin, estrogen, and progesterone stimulate breast milk development. Following childbirth, prolactin helps initiate and maintain the breast milk supply. If a woman does not breastfeed, her prolactin level soon drops back to pre-pregnancy levels. If she does nurse, suckling by the infant plays an important role in the release of prolactin. There is a feedback mechanism between how often the baby nurses and the amount of prolactin secreted by the pituitary as well as the amount of milk produced. Another common cause of elevated prolactin levels is a prolactinoma, a prolactin-producing tumor of the pituitary gland. Prolactinomas are the most common type of pituitary tumor and are usually benign. They develop more frequently in women but are also found in men. Problems resulting from them can arise both from the unintended effects of excess prolactin, such as milk production in the non-pregnant woman (and rarely, man) and from the size and location of the tumor. If the anterior pituitary gland and/or the tumor enlarge significantly, it can put pressure on the optic nerve, causing headaches and visual disturbances, and it can interfere with the other hormones that the pituitary gland produces. In women, prolactinomas can cause infertility and irregularities in menstruation; in men, these tumors can cause a gradual loss in sexual function and libido. If left untreated, prolactinomas may eventually damage the tissues around them.

Also known as: Testosterone, Testosterone Total LCMSMS, Testosterone, Total

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

TSH

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The Women's Hormone Test Panel — Basic panel contains 6 tests with 8 biomarkers .

The Women's Hormone Test Panel — Basic is a comprehensive blood test designed to evaluate key hormone levels in women. Hormones play a crucial role in regulating various physiological processes, including reproductive health, metabolism, mood, and overall well-being. An imbalance in these hormones can indicate underlying health issues or explain specific symptoms such as irregular menstrual cycles, fertility concerns, fatigue, or mood disturbances. This panel provides critical insights into the hormonal health of women, offering a snapshot of the endocrine system's function.

When and Why the Women's Hormone Test Panel — Basic May Be Ordered

The Women's Hormone Test Panel — Basic may be ordered when a woman experiences symptoms that suggest hormonal imbalances or dysfunction. Healthcare providers often recommend this panel for women dealing with issues like irregular menstrual cycles, infertility, menopause symptoms, unexplained weight gain, persistent fatigue, or abnormal hair growth. It is also used to monitor hormone levels in women undergoing hormone replacement therapy or treatments for polycystic ovary syndrome (PCOS) and other endocrine disorders.

This panel is often ordered when a doctor suspects conditions such as thyroid disorders, ovarian dysfunction, or adrenal abnormalities. It can help evaluate the overall hormonal status of a patient and pinpoint imbalances that may be contributing to symptoms.

What the Women's Hormone Test Panel — Basic Checks For

The Women's Hormone Test Panel — Basic measures a range of hormones that play essential roles in reproductive and overall health. Each hormone within the panel provides specific information about the body's endocrine function:

DHEA Unconjugated

Dehydroepiandrosterone (DHEA) is an adrenal steroid hormone produced primarily in the adrenal glands. It serves as a precursor to other sex hormones, such as estrogen and testosterone. DHEA levels naturally decline with age, but abnormal levels can indicate adrenal gland disorders or conditions like polycystic ovary syndrome (PCOS).

Estradiol

Estradiol is the primary form of estrogen in premenopausal women. It plays a critical role in the menstrual cycle, fertility, and the maintenance of secondary sexual characteristics. Abnormal estradiol levels may indicate menopause, ovarian dysfunction, or estrogen-related disorders.

Follicle-Stimulating Hormone (FSH)

FSH is produced by the pituitary gland and is essential for the development of ovarian follicles and regulation of the menstrual cycle. Elevated FSH levels are commonly seen in menopause, while low levels may indicate pituitary or ovarian dysfunction.

Luteinizing Hormone (LH)

LH works in conjunction with FSH to regulate the menstrual cycle and ovulation. High LH levels can indicate polycystic ovary syndrome (PCOS), menopause, or primary ovarian failure, while low levels may suggest pituitary dysfunction.

Prolactin

Prolactin is produced by the pituitary gland and is responsible for stimulating milk production after childbirth. Elevated prolactin levels outside of pregnancy or breastfeeding can indicate pituitary tumors, hypothyroidism, or other endocrine disorders.

Testosterone Total

Testosterone is primarily thought of as a male hormone, but it is also present in women and plays a role in libido, energy, and muscle maintenance. High testosterone levels in women may be associated with PCOS or adrenal hyperplasia, while low levels can impact energy levels and overall well-being.

Thyroid-Stimulating Hormone (TSH)

TSH is produced by the pituitary gland to regulate thyroid hormone production. Abnormal TSH levels indicate thyroid dysfunction, such as hypothyroidism or hyperthyroidism, which can affect metabolism, energy, and overall hormonal balance.

Conditions or Diseases the Women's Hormone Test Panel — Basic Can Detect

The Women's Hormone Test Panel — Basic can detect or help diagnose various conditions and diseases related to hormone imbalances. These include polycystic ovary syndrome (PCOS), menopause, thyroid disorders, adrenal dysfunction, and pituitary abnormalities.

Polycystic Ovary Syndrome (PCOS)

PCOS is a hormonal disorder characterized by irregular periods, excessive hair growth, acne, and ovarian cysts. Women with PCOS often have elevated testosterone levels and an imbalance in LH and FSH. This test panel can identify elevated testosterone and LH levels while ruling out other conditions.

Menopause and Perimenopause

Menopause marks the end of a woman’s reproductive years and is associated with decreased estrogen production. The panel detects elevated FSH and LH levels, alongside reduced estradiol levels, confirming menopause or perimenopause. Tracking these hormones can help manage symptoms such as hot flashes, mood swings, and bone loss.

Thyroid Disorders (Hypothyroidism and Hyperthyroidism)

Thyroid dysfunction can cause a variety of symptoms, including fatigue, weight changes, and menstrual irregularities. TSH is a key indicator of thyroid health, with elevated levels suggesting hypothyroidism and low levels pointing to hyperthyroidism. Identifying thyroid disorders allows for proper treatment and management.

Adrenal Dysfunction

Adrenal disorders, such as adrenal insufficiency or adrenal hyperplasia, can cause abnormal DHEA levels. Symptoms include chronic fatigue, weight changes, and hormonal imbalances. The panel assesses DHEA levels to detect adrenal abnormalities and guide treatment.

Pituitary Disorders

The pituitary gland regulates many hormones, including FSH, LH, TSH, and prolactin. Disorders such as pituitary tumors can lead to elevated prolactin levels or abnormal FSH and LH levels. This panel helps evaluate pituitary function and identify imbalances linked to these disorders.

How Healthcare Professionals Use the Results of the Women's Hormone Test Panel — Basic

Managing Polycystic Ovary Syndrome (PCOS)

If elevated testosterone and LH levels are detected, a healthcare professional can confirm a diagnosis of PCOS. Treatment may include lifestyle changes, medications to regulate menstrual cycles, or anti-androgen therapy to address symptoms such as acne and excessive hair growth.

Managing Menopause and Perimenopause

By identifying decreased estradiol levels and elevated FSH and LH levels, healthcare providers can confirm menopause or perimenopause. Treatment options include hormone replacement therapy (HRT) to alleviate symptoms, as well as lifestyle interventions to manage bone health and cardiovascular risks.

Treating Thyroid Disorders

For patients with abnormal TSH levels, healthcare professionals may prescribe thyroid hormone replacement for hypothyroidism or anti-thyroid medications for hyperthyroidism. Monitoring hormone levels ensures that thyroid function remains stable and symptoms are managed effectively.

Addressing Adrenal Dysfunction

When abnormal DHEA levels are identified, healthcare providers may conduct further tests to evaluate adrenal function. Treatment may involve hormone replacement therapy, stress management strategies, or medications to regulate adrenal hormones.

Managing Pituitary Disorders

Elevated prolactin levels or abnormal FSH and LH levels may prompt further imaging studies to assess for pituitary tumors. Treatment may include medications to normalize hormone levels or surgical intervention in severe cases.

Conclusion

The Women's Hormone Test Panel — Basic is an invaluable tool for assessing hormone levels and identifying underlying conditions that may impact a woman's health. By measuring key hormones, this panel provides insights into reproductive function, thyroid health, adrenal function, and pituitary gland activity. It helps diagnose conditions such as PCOS, menopause, thyroid disorders, and adrenal or pituitary abnormalities. Healthcare providers can use the results to guide targeted treatments, improve symptom management, and promote overall well-being in women experiencing hormonal imbalances.

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