Female Fertility Blood and Urine Test Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Estradiol

Estradiol (estradiol-17 beta, E2) is part of an estrogen that is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men. Estradiol (E2) is the predominant form of estrogen and is produced primarily in the ovaries with additional amounts produced by the adrenal glands in women and in the testes and adrenal glands in men. Estradiol levels are used in evaluating ovarian function. Estradiol levels are increased in cases of early (precocious) puberty in girls and gynecomastia in men. Its main use has been in the differential diagnosis of amenorrhea – for example, to determine whether the cause is menopause, pregnancy, or a medical problem. In assisted reproductive technology (ART), serial measurements are used to monitor follicle development in the ovary in the days prior to in vitro fertilization. Estradiol is also sometimes used to monitor menopausal hormone replacement therapy.

Also known as: Estrogen Total Serum

Estrogen, Total, Serum

Estrogen is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men.

Also known as: Follicle Stimulating Hormone, FSH Follicle Stimulating Hormone

Fsh

Also known as: Progesterone Immunoassay

Progesterone

Serum progesterone is a test to measure the amount of progesterone in the blood. Progesterone is a hormone produced mainly in the ovaries. In women, progesterone plays a vital role in pregnancy. After an egg is released by the ovaries (ovulation), progesterone helps make the uterus ready for implantation of a fertilized egg. It prepares the womb (uterus) for pregnancy and the breasts for milk production. Men produce some amount of progesterone, but it probably has no normal function except to help produce other steroid hormones.

Also known as: PRL

Prolactin

Prolactin is a hormone produced by the anterior portion of the pituitary gland, a grape-sized organ found at the base of the brain. Prolactin secretion is regulated and inhibited by the brain chemical dopamine. Normally present in low amounts in men and non-pregnant women, prolactin's primary role is to promote lactation (breast milk production). Prolactin levels are usually high throughout pregnancy and just after childbirth. During pregnancy, the hormones prolactin, estrogen, and progesterone stimulate breast milk development. Following childbirth, prolactin helps initiate and maintain the breast milk supply. If a woman does not breastfeed, her prolactin level soon drops back to pre-pregnancy levels. If she does nurse, suckling by the infant plays an important role in the release of prolactin. There is a feedback mechanism between how often the baby nurses and the amount of prolactin secreted by the pituitary as well as the amount of milk produced. Another common cause of elevated prolactin levels is a prolactinoma, a prolactin-producing tumor of the pituitary gland. Prolactinomas are the most common type of pituitary tumor and are usually benign. They develop more frequently in women but are also found in men. Problems resulting from them can arise both from the unintended effects of excess prolactin, such as milk production in the non-pregnant woman (and rarely, man) and from the size and location of the tumor. If the anterior pituitary gland and/or the tumor enlarge significantly, it can put pressure on the optic nerve, causing headaches and visual disturbances, and it can interfere with the other hormones that the pituitary gland produces. In women, prolactinomas can cause infertility and irregularities in menstruation; in men, these tumors can cause a gradual loss in sexual function and libido. If left untreated, prolactinomas may eventually damage the tissues around them.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Testosterone, Testosterone Total LCMSMS, Testosterone, Total

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

TSH

Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete

Amorphous Sediment

Appearance

Bacteria

Bacteria are living things that have only one cell. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli.

Bilirubin

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Calcium Oxalate Crystals

Calcium oxalate is a chemical compound that forms envelope-shaped crystals. A major constituent of human kidney stones.

Casts

Urinary casts are cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Color

Crystals

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Granular Cast

The second-most common type of cast, granular casts can result either from the breakdown of cellular casts or the inclusion of aggregates of plasma proteins (e.g., albumin) or immunoglobulin light chains. Depending on the size of inclusions, they can be classified as fine or coarse, though the distinction has no diagnostic significance. Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise

Hyaline Cast

Urinary casts are tiny tube-shaped particles. Urinary casts may be made up of white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The most common type of cast, hyaline casts are solidified Tamm-Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and, as such, they may be seen in normal individuals in dehydration or vigorous exercise. Hyaline casts are cylindrical and clear, with a low refractive index,

Ketones

Ketones are substances produced in the liver when fat cells break down in the blood. A serum ketone test is a measurement of how many ketones are in the blood.

Leukocyte Esterase

Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.

Nitrite

Occult Blood

The test looks for hidden (occult) blood in a specimen sample. It can find blood even if you cannot see it yourself.

Ph

Level of acid

Protein

Body fluids contain many different proteins that serve diverse functions such as transport of nutrients, removal of toxins, control of metabolic processes, and defense against invaders. Protein electrophoresis is a method for separating these proteins based on their size and electrical charge. When body fluids are separated by electrophoresis, they form a characteristic pattern of bands of different widths and intensities, reflecting the mixture of proteins present. This pattern is divided into five fractions, called albumin, alpha 1, alpha 2, beta, and gamma. In some cases, the beta fraction is further divided into beta 1 and beta 2. Albumin, which is produced in the liver, accounts for about 60% of the protein in the blood. "Globulins" is a collective term used to refer to proteins other than albumin. With the exception of the immunoglobulins and some complement proteins, most of the globulins are also produced in the liver. Immunofixation electrophoresis (IFE) is a method used to identify abnormal bands seen on serum, urine, or CSF protein electrophoresis, as to which type of antibody (immunoglobulin) is present.

Rbc

RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

Reducing Substances

Renal Epithelial Cells

Specific Gravity

Squamous Epithelial Cells

Transitional Epithelial

Triple Phosphate Crystals

Struvite stones (triple phosphate/magnesium ammonium phosphate) - about 10–15% of urinary calculi are composed of struvite (ammonium magnesium phosphate, NH4MgPO4·6H2O).[44] Struvite stones (also known as "infection stones", urease or triple-phosphate stones), form most often in the presence of infection by urea-splitting bacteria

Uric Acid Crystals

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

WBC

WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

YEAST

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.
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The Female Fertility Blood and Urine Test Panel panel contains 9 tests with 36 biomarkers .

Female Fertility Blood and Urine Test Panel

The Female Fertility Blood and Urine Test Panel is designed to evaluate key hormonal and metabolic markers that influence reproductive health. This panel assesses the function of the thyroid, adrenal glands, ovaries, and overall hormonal balance, providing insight into fertility potential and menstrual cycle regulation. Additionally, the panel includes a urinalysis to detect infections, kidney function issues, and metabolic abnormalities that could impact reproductive health. By analyzing these biomarkers, healthcare providers can identify underlying conditions that may contribute to infertility, irregular menstrual cycles, or other reproductive concerns.

When and Why the Female Fertility Blood and Urine Test Panel May Be Ordered

This panel is typically ordered for women who are experiencing difficulty conceiving, irregular menstrual cycles, or symptoms of hormonal imbalance such as unexplained weight changes, mood disturbances, or changes in libido. It may also be recommended for women with a history of polycystic ovary syndrome (PCOS), thyroid disorders, or other endocrine conditions that can affect fertility. Women undergoing fertility treatments, such as in-vitro fertilization (IVF) or ovulation induction, may use this panel to monitor their hormone levels and optimize their chances of conception. Additionally, this test can help identify potential infections or metabolic disorders that may impact reproductive health.

What the Female Fertility Blood and Urine Test Panel Checks For

The Female Fertility Blood and Urine Test Panel evaluates various hormones and metabolic markers that influence reproductive health, menstrual cycle regulation, and overall well-being. Each test in the panel provides essential information to assess hormonal balance and reproductive function.

Thyroid Function and Its Role in Fertility

Thyroid hormones play a crucial role in regulating metabolism and reproductive health. An imbalance in thyroid function can lead to menstrual irregularities, ovulatory dysfunction, and infertility. By measuring thyroid hormone levels, this panel helps determine whether an individual has hypothyroidism, hyperthyroidism, or other thyroid disorders that may be impacting fertility.

Ovarian Function and Hormonal Balance

Hormones such as estrogen, progesterone, follicle-stimulating hormone (FSH), and prolactin are vital for normal ovarian function and menstrual cycle regulation. This panel assesses these hormones to determine if ovulation is occurring properly and whether there are imbalances that could affect fertility.

Androgen Levels and Their Effect on Fertility

Androgens, including testosterone and DHEA-S, play a role in ovarian function and overall reproductive health. Elevated androgen levels are commonly associated with conditions such as PCOS, which can disrupt ovulation and contribute to infertility. By measuring these hormones, the panel helps identify whether androgen excess is a factor in reproductive issues.

Urinalysis for Infection and Metabolic Health

A complete urinalysis is included in this panel to detect urinary tract infections (UTIs), kidney function abnormalities, and metabolic conditions such as diabetes. Undiagnosed infections or metabolic imbalances can interfere with reproductive health, making urinalysis a valuable component of fertility assessment.

Conditions and Diseases the Female Fertility Blood and Urine Test Panel Can Detect

This panel is useful in diagnosing various conditions that affect fertility, menstrual cycle regularity, and overall reproductive health. Early detection of these conditions allows for appropriate treatment and management strategies.

Polycystic Ovary Syndrome (PCOS)

PCOS is a common hormonal disorder that affects ovulation and fertility. It is characterized by irregular menstrual cycles, excess androgen levels, and ovarian cysts. This panel helps diagnose PCOS by measuring testosterone, DHEA-S, estrogen, and FSH levels. Elevated androgens and an imbalance between estrogen and FSH can indicate PCOS, guiding appropriate treatment options.

Hypothyroidism and Hyperthyroidism

Thyroid dysfunction can have a significant impact on fertility. Hypothyroidism (underactive thyroid) can lead to irregular ovulation, while hyperthyroidism (overactive thyroid) can cause menstrual disturbances and pregnancy complications. This panel detects thyroid imbalances by measuring TSH and free T4 levels.

Luteal Phase Deficiency

Luteal phase deficiency occurs when the body does not produce enough progesterone after ovulation, leading to implantation failure and early pregnancy loss. This panel assesses progesterone levels to determine if supplementation or treatment is needed to support a healthy pregnancy.

Prolactin Imbalance

Prolactin is a hormone that regulates milk production but can also impact fertility. High prolactin levels can suppress ovulation and lead to menstrual irregularities. By measuring prolactin levels, this panel helps identify hyperprolactinemia and guides treatment strategies to restore fertility.

Adrenal Disorders

The adrenal glands produce hormones that influence reproductive health. An imbalance in adrenal hormones, such as elevated DHEA-S, can contribute to conditions like PCOS and infertility. This panel assesses adrenal function to determine if excess androgen production is affecting reproductive health.

Urinary Tract Infections and Kidney Function Issues

Undiagnosed UTIs or kidney function abnormalities can impact reproductive health and cause complications during pregnancy. The urinalysis component of this panel detects infections, protein imbalances, and metabolic markers that may require medical attention.

How Healthcare Professionals Use the Female Fertility Blood and Urine Test Panel in Treatment and Monitoring

Healthcare providers use this panel to diagnose and manage reproductive health conditions, guiding treatment strategies to improve fertility and overall well-being.

Managing PCOS and Restoring Ovulation

If PCOS is detected, treatment options may include lifestyle modifications, medications such as metformin, or ovulation-inducing drugs like clomiphene citrate. Monitoring hormone levels helps track progress and ensure effective management of the condition.

Treating Thyroid Disorders

For patients diagnosed with hypothyroidism or hyperthyroidism, thyroid hormone therapy may be prescribed to restore normal function. Regular monitoring of TSH and free T4 levels ensures that treatment is effective and supports reproductive health.

Addressing Luteal Phase Deficiency

If low progesterone levels are detected, progesterone supplementation may be recommended to support the uterine lining and improve implantation success for those trying to conceive.

Reducing Prolactin Levels

If high prolactin levels are found, treatment with dopamine agonists such as bromocriptine or cabergoline may be used to lower prolactin and restore normal ovulatory function.

Managing Adrenal Hormone Imbalances

If adrenal dysfunction is detected, treatment may include lifestyle changes, stress management, or medications to regulate androgen production and support normal reproductive function.

Treating UTIs and Addressing Kidney Function Concerns

If a UTI or kidney function abnormality is identified, antibiotics or other appropriate treatments may be prescribed to eliminate infection and prevent complications that could affect fertility and pregnancy.

Conclusion

The Female Fertility Blood and Urine Test Panel is an essential diagnostic tool for assessing reproductive health, hormone balance, and metabolic function. By evaluating thyroid function, ovarian hormones, androgen levels, and urinary health, this panel provides valuable insights into potential fertility challenges and guides treatment options. Early detection and appropriate management of conditions such as PCOS, thyroid disorders, luteal phase deficiency, and infections can improve reproductive outcomes and overall well-being, helping individuals on their journey toward conception and hormonal balance.

 

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