Infection STD Tests

Sexually transmitted infections (STIs), often called STDs, can be silent or cause symptoms like discharge, sores, or pelvic pain. Because many STIs overlap in symptoms—or have no symptoms at alllaboratory testing is the most reliable way to know your status, protect partners, and guide next steps with your clinician.

This page explains evidence-based STI testing for screeningpost-exposure checks, and diagnostic work-ups. It includes HIV (4th-generation Ag/Ab and RNA)syphilis (RPR with treponemal confirmation)chlamydia/gonorr... See more

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 The STD Comprehensive panel offers a broad overview of an individual's sexual health by screening for several prevalent sexually transmitted diseases. This comprehensive approach ensures that both bacterial and viral infections are tested for, providing a detailed picture of potential risks and existing infections, many of which may be asymptomatic.
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 The STD Basic panel is a curated selection of tests aimed at detecting some of the most common sexually transmitted diseases (STDs). These tests employ various laboratory techniques to identify the presence of specific pathogens or the body's immune response to them. By providing insights into an individual's sexual health status, this panel plays a pivotal role in early detection, treatment, and prevention of further transmission of these infections.
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The Chlamydia trachomatis RNA TMA Urine Test detects genetic material of C. trachomatis using transcription-mediated amplification (TMA), a highly sensitive method for diagnosing infection. Doctors order this noninvasive urine test for patients with symptoms like discharge, pain, or burning urination, or for routine STD screening. Results help confirm infection, guide treatment, and prevent complications such as infertility, pelvic inflammatory disease, or transmission.

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Also Known As: Chlamydia Trachomatis Test, Chlamydia STD Test, Chlamydia Urine Test

The Chlamydia/Neisseria gonorrhoeae RNA, TMA Urine Test screens for both chlamydia and gonorrhea infections by detecting RNA from these bacteria. Using advanced molecular technology, it offers high accuracy for diagnosing active infections. Doctors order this urine-based test to confirm infection, support early treatment, and protect sexual partners. It is an essential tool for sexual health screening, helping reduce long-term health risks and control STD spread.

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Also Known As: Gonorrhea and Chlamydia Test

The Chlamydia trachomatis IgM Antibody Test detects IgM antibodies produced during early immune response to C. trachomatis infection. IgM positivity can indicate recent or acute infection, making it useful for identifying new exposure. This test provides valuable diagnostic information for evaluating sexually transmitted infections, guiding management, and supporting early detection of reproductive or urogenital health risks.

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The Cytomegalovirus (CMV) IgG Antibody Test detects IgG antibodies to CMV, indicating past infection or immunity. This blood test helps determine prior exposure, assess immune status in pregnancy, transplant patients, or immunocompromised individuals, and guide risk evaluation. A positive result shows past CMV infection, while results are used with IgM testing to distinguish recent vs. past infection.

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Also Known As: CMV IgG Antibody Test, Cytomegalovirus IgG Test

The Cytomegalovirus (CMV) IgM Antibody Test detects IgM antibodies, indicating a recent or active CMV infection. This blood test helps diagnose primary CMV, reactivation, or reinfection, especially important for pregnant women, transplant candidates, and immunocompromised patients. Used with CMV IgG testing, it helps distinguish new infections from past exposure for accurate clinical evaluation.

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Also Known As: CMV IgM Antibody Test, Cytomegalovirus IgM Test

The Neisseria gonorrhoeae RNA TMA Urine Test detects gonorrhea infection by identifying bacterial RNA using transcription-mediated amplification. This highly sensitive urine test helps diagnose current gonorrhea infections, even in asymptomatic cases. Doctors use it for early detection, accurate diagnosis, and timely treatment to prevent complications. Results support effective STD management and help reduce the risk of transmission.

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Also Known As: GC Test, Neisseria Gonorrhoeae test, Gonorrhoeae test, Gonorrhea Urine Test

The Herpes 1 and 2 Test uses type-specific HSV-1/HSV-2 IgG to assess past infection and differentiate exposure to each virus. It is useful for evaluating recurrent lesions, screening asymptomatic partners, and documenting baseline status for clinical management. Because IgG can take 2–12 weeks to develop, early negatives may need repeat testing; HSV-2 reactive results reflex to an inhibition assay to verify specificity and reduce cross-reactivity.

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The Herpes 1 IgG Antibody Test detects IgG antibodies to HSV-1, the virus that commonly causes oral herpes (cold sores). IgG develops weeks after exposure and remains for life, making this test useful for confirming past infection and exposure history. Doctors order it for patients with oral sores, blisters, or concerns about herpes transmission. Results help confirm HSV-1 infection, guide treatment, and support counseling and prevention strategies.

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Also Known As: Herpes Simplex Virus 1 IgG Type-Specific Antibody HerpeSelect® Test, Herpes 1 IgG Test, Oral Herpes Test

The Herpes 2 IgG Antibody Test detects IgG antibodies to HSV-2, the virus that most often causes genital herpes. IgG develops weeks after infection and remains for life, making this test valuable for confirming past exposure or infection history. Doctors order it for patients with genital sores, blisters, or concerns about herpes transmission. Results help confirm HSV-2 infection, guide treatment, and support counseling, prevention, and long-term care.

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Also Known As: Herpes Simplex Virus 2 IgG HerpeSelect® Test with Reflex to HSV 2 Inhibition, Herpes 2 IgG Test, Genital Herpes Test

The Herpes Simplex Virus 1 IgG Type-Specific Antibody HerpeSelect® Test detects IgG antibodies to HSV-1, the virus commonly associated with oral herpes. A positive result indicates past exposure, as IgG develops weeks after infection and remains for life. Doctors use this test to confirm HSV-1 infection, evaluate unexplained sores, or guide sexual health management. Results provide essential insight into infection history, immune response, and long-term HSV-1 status.

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Also Known As: Herpes 1 Test, Herpes 1 IgG Test, Oral Herpes Test

The Herpes Simplex Virus 1 and 2 IgG Type-Specific Antibody HerpeSelect® Test detects IgG antibodies to HSV-1 and HSV-2, distinguishing between the two types. A positive result indicates past exposure, as IgG develops weeks after infection and remains long-term. Doctors use this test to confirm herpes diagnosis, guide treatment, or support sexual health decisions. Results provide vital insight into HSV status, infection history, and long-term immune response.

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Also Known As: Herpes 1 and 2 Test, Herpes IgG Test

The Herpes Virus 6 DNA Test detects HHV-6 DNA in blood or tissue to evaluate active infection or viral reactivation. Human herpesvirus 6 is associated with roseola in children and has been linked to encephalitis, seizures, myocarditis, chronic fatigue, and transplant complications. This molecular test helps assess viral load, monitor disease progression, and guide evaluation of neurological and immunological conditions.


The Herpes Virus 6 IgG IgM Antibodies Test detects immune response to HHV-6, a virus linked to roseola and other illnesses. IgM antibodies suggest recent or acute infection, while IgG indicates past exposure or reactivation. This test supports evaluation of fever, rash, or neurologic symptoms and may help identify complications in immunocompromised patients, providing valuable insight into HHV-6 infection status and immune activity.

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The Histoplasma Galactomannan Antigen Urine Test measures fungal antigens linked to Histoplasma capsulatum infection, which can cause pulmonary or disseminated histoplasmosis. Detection in urine provides a sensitive marker for active disease, particularly in those with weakened immune systems. The test aids clinicians in diagnosis, assessing severity, monitoring therapy, and differentiating histoplasmosis from other fungal infections.

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The Lymphocyte Subset Panel 4 Test measures CD4+ and CD8+ T-cell percentages and absolute counts, along with the CD4/CD8 ratio and total lymphocyte level. These parameters are vital for evaluating immune function in HIV, immunodeficiency, or therapy response, helping track helper and cytotoxic T-cell balance, immune suppression, and immune recovery.

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The RPR Test with Reflex to Titer and Confirmatory Testing screens for syphilis by detecting non-treponemal antibodies. If reactive, results are automatically followed by a titer to measure antibody concentration and confirmatory treponemal testing for accuracy. Doctors use this test to diagnose active or past syphilis, monitor treatment, or screen at-risk patients. Results provide vital insight into infection status, disease stage, and overall sexual health.

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Also Known As: Syphilis Test, Rapid Plasma Reagin Test

The Syphilis Test is an RPR Test with Reflex to Titer and Confirmatory Testing that screens for antibodies to Treponema pallidum. If reactive, additional testing confirms infection and measures antibody levels to assess disease activity. Doctors use this blood test to diagnose syphilis, determine stage, and monitor treatment response. It is widely used in STD screening, prenatal care, and early detection to prevent complications and transmission.

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Also Known As: RPR Test with Reflex to Titer and Confirmatory Testing, Rapid Plasma Reagin Test

The RPR (Monitor) with Reflex to Titer Test screens for syphilis by detecting antibodies to Treponema pallidum. If positive, a reflex titer determines antibody concentration to assess disease activity and treatment response. Doctors order this test to diagnose syphilis, monitor therapy, or check reinfection. Results provide essential information for managing active infection, confirming treatment success, and guiding follow-up care.

Also Known As: Syphilis RPR Test, Rapid Plasma Reagin Test

The Rubella Titer Test measures IgG antibodies to determine immunity to rubella (German measles). A positive result indicates protection from prior infection or vaccination, while a negative result suggests susceptibility. Doctors order this test for women planning pregnancy, healthcare workers, students, or travelers. It helps confirm immune status, guide vaccination needs, and protect against congenital rubella syndrome and outbreak risks.

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Also Known As: Rubella IgG Antibody Test, Rubella Immune Status Test, German Measles Test, 3 Day Measles Test, Three Day Measles Test

The Syphilis (RPR + FTA-ABS) panel is a diagnostic tool used to detect and confirm the presence of syphilis, a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. This panel combines two tests: the RPR (Rapid Plasma Reagin) Screen with Reflex to Titer, and the FTA-ABS (Fluorescent Treponemal Antibody Absorption) test, offering both initial screening and confirmatory diagnosis capabilities.
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The Syphilis FTA-ABS Test (Fluorescent Treponemal Antibody Absorption) detects antibodies specific to Treponema pallidum, the bacteria that cause syphilis. Doctors use this confirmatory test after a positive screening to verify infection, even in late or latent stages. Results help distinguish syphilis from false positives, guiding diagnosis, treatment, and follow-up. This test is essential for accurate detection and long-term monitoring of syphilis.

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Also Known As: Fluorescent Treponemal Antibody Absorption Antibodies Test

The Syphilis RPR Test screens for syphilis by detecting nonspecific antibodies produced in response to Treponema pallidum. If positive, a reflex titer is performed to measure antibody levels and monitor disease activity. Doctors use this blood test to confirm infection, determine stage, and track treatment response. It is widely used for STD screening, prenatal care, and early detection to prevent complications and transmission.

Also Known As: RPR (Monitor) Test with Reflex to Titer, Rapid Plasma Reagin Test

Sexually transmitted diseases in the U.S. have reached an all-time high since 2015! There were approximately 2.6 million cases of STDs in 2019 in the U.S. More than 1.8 million cases of Chlamydia, 129,813 cases of Syphilis, and 616,329 cases of gonorrhea were reported.

Are you taking steps to protect yourself? Are you safe?

In this piece, you'll learn everything you need to know about screening methods and the top tests a patient can ask for STDs. In addition, you'll learn what each STD is and the possible symptoms and signs for each.

Don't hesitate! Continue reading to discover what STD tests you can ask for today for a safer tomorrow.

What Are STDs?

Sexually transmitted diseases (STDs) are infections spread from one individual to another, generally by sexual intercourse (vaginal, anal, and oral). Some common examples of STDs are Gonorrhea, Chlamydia, Herpes ... See more

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STDs And HIV Frequently Asked Questions

Are STDs associated with HIV?

You are more likely to contract HIV or transmit the disease to other sexual partners if you have an STD.

People in the U.S. who have syphilisherpes, ... See more