Ulta Lab Tests

Y Chromosome Microdeletion, DNA Analysis

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Y Chromosome

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The Y Chromosome Microdeletion, DNA Analysis test contains 1 test with 1 biomarker .

The Y Chromosome Microdeletion, DNA Analysis Test is a crucial diagnostic tool designed to investigate genetic factors contributing to male infertility. This test focuses on detecting tiny deletions in the Y chromosome, which are often linked to abnormalities in sperm production. Understanding these deletions is vital for determining specific genetic causes of infertility, aiding in the management and treatment planning for affected individuals.

Test Description

This DNA analysis involves extracting and examining genetic material from a blood sample to identify microdeletions in regions of the Y chromosome known as azoospermia factor (AZF) regions. These regions are critical for sperm development and function. The test specifically looks for deletions in the AZFa, AZFb, and AZFc regions, which are strongly associated with varying degrees of spermatogenic failure, from low sperm count to complete absence of sperm (azoospermia).

Symptoms Leading to Testing

Men who may be recommended for this test often present with:

  • Low sperm count or poor sperm quality
  • Complete absence of sperm in the semen
  • A history of unsuccessful pregnancies with their partner
  • Known family history of male infertility

The Y Chromosome Microdeletion, DNA Analysis Test is an essential tool for clinicians in the field of reproductive health. By pinpointing specific genetic deletions, this test allows for a better understanding of an individual's infertility issues, facilitating tailored treatment approaches. It is recommended for men experiencing unexplained infertility or those with a known family history of similar reproductive challenges.

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