All Stress and Fatigue Tests

All Stress and Fatigue Tests brings together the labs most often used to investigate low energy, burnout, and stress-related symptoms. Because tiredness is multifactorial, we pair HPA-axis checks (cortisol patterns, DHEA-S) with common “look-alikes,” including thyroid imbalanceanemia/iron or B12 deficiencyblood sugar issuesinflammationelectrolyte or liver/kidney problems, and selected hormone markers.

A proactive plan often starts with 8–9 a.m. serum cortisol (± ACTH) ... See more

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The 17-Hydroxypregnenolone Test measures levels of this adrenal steroid precursor in the blood to help evaluate adrenal gland and steroid hormone function. Abnormal results may indicate congenital adrenal hyperplasia, enzyme deficiencies, or adrenal disorders affecting cortisol and androgen production. This test provides valuable insight into hormonal balance and supports the investigation of endocrine and metabolic health conditions.

Serum
Phlebotomist

The 17-Hydroxyprogesterone (17-OHP) Test measures levels of 17-OHP, a hormone made by the adrenal glands, to help diagnose congenital adrenal hyperplasia (CAH) and other adrenal disorders. Elevated levels may indicate enzyme deficiencies affecting cortisol production, while low levels can suggest adrenal insufficiency. Doctors order this test for infants with ambiguous genitalia or adults with irregular periods, infertility, or abnormal androgen symptoms.

Serum
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Also Known As: 17-OHP Test, 17-OH Progesterone Test

The 21-Hydroxylase Antibody Test detects autoantibodies that target the adrenal enzyme 21-hydroxylase, often linked to autoimmune Addison’s disease and adrenal insufficiency. A positive result suggests adrenal gland damage caused by immune attack. Doctors use this blood test to confirm suspected Addison’s disease, evaluate unexplained fatigue or low cortisol, and monitor patients at risk for autoimmune polyglandular syndromes or adrenal failure.


The ACTH Test measures adrenocorticotropic hormone in blood to evaluate pituitary and adrenal gland function. Abnormal ACTH levels may indicate Cushing’s syndrome, Addison’s disease, adrenal tumors, or pituitary disorders. Doctors order this test to investigate symptoms such as fatigue, weight changes, weakness, or high blood pressure. Results provide vital insight into endocrine health, cortisol regulation, and adrenal-pituitary balance.

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Also Known As: Adrenocorticotropic Hormone Test, Corticotropin Test, Cosyntropin Test

Serum
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The Aldosterone 24 Hour Urine Test evaluates adrenal hormone output across 24 hours, offering information about blood pressure regulation, fluid balance, and electrolyte control. Elevated or low levels may suggest primary aldosteronism, adrenal tumors, or secondary hypertension. This test supports assessment of kidney function, cardiovascular health, and endocrine disorders linked to aldosterone imbalance.

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The Aldosterone and Plasma Renin Activity Ratio Test measures levels of aldosterone and renin to assess adrenal and kidney function. An elevated ratio may indicate primary aldosteronism, a common cause of secondary hypertension. Doctors use this test to evaluate patients with high blood pressure, low potassium, or suspected adrenal disorders. Results help diagnose conditions like Conn’s syndrome, guide treatment, and reduce cardiovascular risks from uncontrolled hypertension.

Also Known As: Aldosterone/Plasma Renin Activity Ratio Test, Aldosterone and Renin Activity Test

The ANA Screen IFA with Reflex to Titer and Pattern Test detects antinuclear antibodies in blood to evaluate autoimmune activity. If positive, further testing identifies antibody concentration (titer) and fluorescence pattern, helping diagnose conditions like lupus, rheumatoid arthritis, or Sjögren’s syndrome. Doctors order this test to investigate symptoms such as joint pain, fatigue, rash, or swelling and to guide treatment for autoimmune and connective tissue disorders.

Also Known As: ANA Test, Antinuclear Antibody Screen Test

The Androstenedione Test measures levels of this steroid hormone, produced by the adrenal glands and ovaries or testes, which converts into testosterone and estrogen. Abnormal results may indicate PCOS, adrenal tumors, congenital adrenal hyperplasia, or ovarian/testicular disorders. Doctors order this test for irregular periods, infertility, excess hair growth, or early puberty. Results provide key insight into hormone balance, adrenal function, and reproductive health.

Serum
Phlebotomist
Also Known As: AD Test

The Antiadrenal Antibody Screen With Reflex To Titer detects antibodies targeting adrenal cortex tissue, which may signal autoimmune adrenal disease. Positive results are reflexed to titer to confirm antibody levels. This test supports diagnosis of Addison’s disease, autoimmune adrenalitis, or endocrine disorders, offering insight into adrenal gland health, immune system activity, and hormone regulation.


The C-Reactive Protein (CRP) Test measures CRP levels in blood to detect inflammation in the body. Elevated CRP may indicate infections, autoimmune disorders, or chronic diseases such as arthritis, cardiovascular disease, or inflammatory bowel disease. Doctors use this test to assess acute illness, monitor treatment response, and evaluate risk for heart disease. The CRP test provides key insight into inflammation, immune health, and overall wellness.

Serum
Phlebotomist
Also Known As: CRP Test, Inflammation Test

The Calcium Micronutrient Test measures calcium levels in the blood to assess nutritional status and detect imbalances. Calcium is essential for strong bones and teeth, muscle contraction, nerve signaling, and heart function. This test helps identify deficiencies, excess, or issues with absorption and metabolism, supporting diagnosis and management of bone health, hormonal balance, and overall wellness.

Patient must be 18 years of age or older.
Serum
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Also Known As: Ca Test, Serum Calcium Test, Calcium Blood Test

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The Calcium Test measures calcium levels in blood to assess bone health, parathyroid function, and metabolic balance. Abnormal levels may indicate bone disease, parathyroid disorders, kidney disease, or certain cancers. Both low and high calcium can cause muscle spasms, weakness, or irregular heartbeat. Doctors order this test to monitor osteoporosis, kidney stones, or endocrine disorders. Results provide essential insight into bone, nerve, and overall metabolic health.

Serum
Phlebotomist
Also Known As: Ca Test, Serum Calcium Test, Calcium Blood Test

The Heavy Metals Micronutrients Blood Test Panel measures levels of arsenic, cadmium, cobalt, lead, and mercury to assess exposure and potential toxicity. These metals, found in the environment, food, or workplaces, can affect the nervous system, kidneys, bones, and overall health. This panel helps detect harmful accumulation, guide treatment, and monitor risks from environmental or occupational exposure.

Patient must be 18 years of age or older.

The Cardio IQ™ HDL Cholesterol Test evaluates levels of high-density lipoprotein cholesterol, the “good” cholesterol that plays a critical role in heart health. Adequate HDL supports the removal of excess cholesterol from the bloodstream, reducing plaque buildup in arteries. This test provides valuable insight into cardiovascular wellness, lipid balance, and overall risk of heart disease when combined with other lipid panel results.

Serum
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The Cardio IQ™ Lipoprotein Fractionation Ion Mobility Test separates and measures lipoprotein particles by size and concentration using ion mobility technology. It provides a detailed profile of LDL, HDL, and other subclasses, offering a clearer assessment of cardiovascular risk than standard cholesterol testing.

Serum
Phlebotomist
Also Known As: LDL Particle Testing, LDL Subclass Test, LDL Fractionations Test

The NMR Lipoprotein Fractionation Test uses nuclear magnetic resonance to measure particle size and concentration of LDL, HDL, and VLDL cholesterol. Unlike a standard lipid panel, it provides detailed information on lipoprotein subfractions linked to cardiovascular risk. Doctors use this test to assess heart disease risk, guide cholesterol management, and monitor therapy effectiveness. It offers deeper insight into lipid metabolism and cardiovascular health.

Serum
Phlebotomist
Also Known As: NMR Test, LDL Particle Testing, LDL Subclass Test, LDL Fractionations Test

The Cardio IQ Vitamin D test, also known as a 25-hydroxy vitamin D test, measures the levels of total vitamin D in the blood, including both vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). It provides information about an individual's overall vitamin D status.

Serum
Phlebotomist
Also Known As: Ergocalciferol Test, Vitamin D2 Test, Cholecalciferol Test, Vitamin D3 Test, Calcidiol Test, 25-hydroxyvitamin D Test, Calcifidiol Test, 25-hydroxy-vitamin D Test

The HDL Cholesterol Test measures high-density lipoprotein cholesterol, often called “good” cholesterol, which helps remove excess cholesterol from the bloodstream. Higher HDL levels are linked to a lower risk of heart disease, while low levels may increase cardiovascular risk. Doctors use this blood test as part of a lipid panel to assess heart health, evaluate risk factors, and guide lifestyle or treatment strategies for cardiovascular disease prevention.

Serum
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Also Known As: Good Cholesterol Test

A shocking statistic you may not know is that 55 percent of Americans experience stress during the day. That’s about one in two people! 

It’s a statistic that should get one concerned, considering what stress can do to our bodies. 

If you feel overwhelmed by stress in your day-to-day life, you should consider a stress lab test. A lab test can check various biomarkers that can help establish whether or not your well-being is taking a hit from your level of stress. 

Let’s start by learning more about stress.

What is Stress? 

Stress is the body’s reaction upon being put under pressure by internal or external stimuli. Whenever your body responds to stressful stimuli, you may have a physical, emotional, or mental response. 

It is normal for every person to deal with stress at a point in their life. ... See more