Methylation Panel
- $2,043.83
- $589
- Save: 71.18%
The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: Amino Acid Analysis LCMS Plasma
1-Methylhistidine
3-Methylhistidine
Alanine
Alpha Amino Adipic Acid
Alpha Amino Butyric Acid
Arginine
Asparagine
Aspartic Acid
Beta Amino Isobutyric
Beta-Alanine
Citrulline
Cystathionine
Date Of Birth
Ethanolamine
Gamma Amino Butyric Acid
Glutamic Acid
Glutamine
Glycine
Histidine
Homocystine
Hydroxyproline
Interpretation
Isoleucine
Leucine
Lysine
Methionine
Ornithine
Phenylalanine
Proline
Sarcosine
Serine
Taurine
Threonine
Tryptophan
Tyrosine
Valine
Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)
NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.
Absolute Band Neutrophils
Absolute Basophils
Absolute Blasts
Absolute Eosinophils
Absolute Lymphocytes
Absolute Metamyelocytes
Absolute Monocytes
Absolute Myelocytes
Absolute Neutrophils
Absolute Nucleated Rbc
Absolute Promyelocytes
Band Neutrophils
Basophils
Blasts
Eosinophils
Hematocrit
Hemoglobin
Lymphocytes
MCH
MCHC
MCV
Metamyelocytes
Monocytes
MPV
Myelocytes
Neutrophils
Nucleated Rbc
Platelet Count
Promyelocytes
RDW
Reactive Lymphocytes
Red Blood Cell Count
White Blood Cell Count
Also known as: Chem 12, Chemistry Panel, Chemistry Screen, CMP, Complete Metabolic Panel, Comprehensive Metabolic Panel CMP, SMA 12, SMA 20
Albumin
Albumin/Globulin Ratio
Alkaline Phosphatase
Alt
AST
Bilirubin, Total
Bun/Creatinine Ratio
Calcium
Carbon Dioxide
Chloride
Creatinine
Egfr African American
Egfr Non-Afr. American
GFR-AFRICAN AMERICAN
GFR-NON AFRICAN AMERICAN
Globulin
Glucose
Potassium
Protein, Total
Sodium
Urea Nitrogen (Bun)
Also known as: Folate Serum, Folic Acid
Folate, Serum
Also known as: Homocysteine, Homocysteine Cardiovascular
HOMOCYSTEINE,
Also known as: Methylenetetrahydrofolate Reductase MTHFR DNA Mutation Analysis, MTHFR
Methylenetetrahydrofolate
RESULT
Methylmalonic Acid
Also known as: B12, B12 Vitamin, Cobalamin, Cyanocobalamin, Vitamin B12 Cobalamin
Vitamin B12
The Methylation Panel panel contains 8 tests with 96 biomarkers .
The Methylation Panel is designed to provide insights into the body's methylation process, which is a crucial biochemical pathway that involves the transfer of a methyl group (one carbon atom and three hydrogen atoms) onto amino acids, proteins, enzymes, and DNA in every cell and tissue of the body.
This process is vital for numerous bodily functions, including detoxification, energy production, immune function, mood balancing, and controlling inflammation. An optimal methylation process is essential for DNA repair and gene expression regulation.
The Methylation Panel includes a series of tests that provide comprehensive insight into the methylation process and related biochemical pathways in the body. Below is a detailed description of each component:
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Amino Acid Analysis, LC/MS, Plasma:
- This test measures the concentration of amino acids in the plasma using Liquid Chromatography-Mass Spectrometry (LC/MS). It evaluates both essential and non-essential amino acids and can detect imbalances that may affect the methylation process and overall metabolic health.
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CBC (Complete Blood Count) (includes Differential and Platelets):
- A CBC is a broad screening test to check for a wide range of disorders, including anemia, infection, and many other diseases. It includes a count of your white blood cells, red blood cells, and platelets, providing information on the cells involved in methylation such as lymphocytes.
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Comprehensive Metabolic Panel (CMP):
- The CMP provides important information about the current status of your metabolism, including kidney and liver health, blood sugar and blood protein levels, and electrolyte and fluid balance.
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Folate, Serum:
- This test measures the level of folate in the serum. Folate is a B-vitamin necessary for the normal production of red blood cells, repair of tissues and cells, and synthesis of DNA, which is crucial for methylation.
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Homocysteine:
- Homocysteine is an amino acid in the blood that can be a marker of the risk of heart disease if elevated. High levels may also suggest vitamin B12 or folate deficiency and problems with methylation.
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Methylenetetrahydrofolate Reductase (MTHFR), DNA Mutation Analysis:
- This genetic test looks for mutations in the MTHFR gene, which provides instructions for making an enzyme that plays a role in processing amino acids and is important for a chemical reaction involving forms of folate. Mutations in this gene are linked to a variety of health issues, including heart disease and birth defects.
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Methylmalonic Acid:
- Methylmalonic acid is used to diagnose vitamin B12 deficiency. Elevated levels can indicate a B12 deficiency, which can lead to problems with DNA synthesis and red blood cell formation, among other issues.
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Vitamin B12 (Cobalamin):
- This test measures the level of vitamin B12 in the blood. B12 is essential for normal blood, cells, and nerves. Deficiencies can lead to a variety of health problems, including certain types of anemia and neuropathy, and can reflect poor methylation capacity.
Collectively, these tests in the Methylation Panel can give a comprehensive view of your body’s methylation capabilities and potential related deficiencies or imbalances, which can be crucial for personalized health strategies.
The Methylation Panel is a comprehensive set of tests that can be used to evaluate an individual's health in the context of a variety of conditions, particularly those that may be influenced by or result in alterations of the body's methylation processes. Here are several conditions where such a panel might be used for evaluation:
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Cardiovascular Diseases: Elevated homocysteine levels are a risk factor for cardiovascular diseases. Testing for homocysteine, along with folate and vitamin B12 levels, can help assess cardiovascular risk and the need for nutritional intervention.
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Neurological Disorders: Conditions like Alzheimer’s disease, Parkinson’s disease, and other cognitive disorders may be related to methylation imbalances. The amino acid analysis, along with B vitamins status, can be critical for these evaluations.
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Mood Disorders: Depression, bipolar disorder, and schizophrenia have been linked to methylation processes. The balance of neurotransmitters is affected by amino acid levels and B vitamins, which are involved in the synthesis of these neurotransmitters.
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Chronic Fatigue Syndrome: This syndrome may be associated with disruptions in metabolic processes, including methylation. A comprehensive metabolic panel can shed light on the underlying metabolic state.
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Autism Spectrum Disorder (ASD): Some research suggests that children with ASD may have unique methylation patterns, which could be detected with this panel.
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Fertility and Pregnancy: Proper methylation is critical for fetal development. MTHFR mutations, folate, and B12 status are particularly important for women who are pregnant or trying to conceive.
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Bone Health: Methylation affects bone density by influencing homocysteine levels; elevated homocysteine has been associated with an increased risk of fractures.
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Autoimmune Disorders: Conditions like rheumatoid arthritis and lupus can be influenced by methylation, as it plays a role in the regulation of the immune system.
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Cancer: Aberrant DNA methylation patterns are a feature of many cancers, and understanding an individual's methylation capacity may be relevant in the context of cancer risk and management.
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Detoxification Issues: Methylation is critical for detoxification pathways in the liver, and the panel could help assess liver function and the body's ability to process and eliminate toxins.
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Developmental Disorders and Birth Defects: Proper methylation is crucial during embryonic development. Testing for MTHFR mutations and levels of related vitamins can be important for assessing risk for developmental disorders and certain birth defects.
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Anemias: Both B12 and folate deficiencies can lead to different types of anemia, which can be assessed by this panel.
This panel provides insights into an individual's methylation status and can help guide treatment decisions and lifestyle adjustments for the conditions listed. It's important to note that methylation is just one aspect of these complex conditions, and the results of these tests should be interpreted by a healthcare professional in the context of the individual’s overall health picture.