Advanced Blood Sugar Monitoring - Comprehensive

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Adiponectin

Also known as: 4 HR Glucose Tolerance, Non-pregnant,, 4 HR GTT (5 Specimens), Glucose Tolerance 4 HR, Non-pregnant, Glucose Tolerance Test 5 Specimens

Glucose, Specimen 1

Glucose, Specimen 2

Glucose, Specimen 3

Glucose, Specimen 4

Glucose, Specimen 5

Glucose, Time 1

Also known as: Glutamic Acid Decarboxylase65 Antibody

Glutamic Acid

GLUTAMIC ACID

Also known as: A1c, Glycated Hemoglobin, Glycohemoglobin, Glycosylated Hemoglobin, HA1c, HbA1c, Hemoglobin A1c, Hemoglobin A1c HgbA1C, Hgb A1c

Hemoglobin A1c

The A1c test evaluates the average amount of glucose in the blood over the last 2 to 3 months. It does this by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein found inside red blood cells (RBCs). There are several types of normal hemoglobin, but the predominant form – about 95-98% – is hemoglobin A. As glucose circulates in the blood, some of it spontaneously binds to hemoglobin A. The hemoglobin molecules with attached glucose are called glycated hemoglobin. The higher the concentration of glucose in the blood, the more glycated hemoglobin is formed. Once the glucose binds to the hemoglobin, it remains there for the life of the red blood cell – normally about 120 days. The predominant form of glycated hemoglobin is referred to as HbA1c or A1c. A1c is produced on a daily basis and slowly cleared from the blood as older RBCs die and younger RBCs (with non-glycated hemoglobin) take their place. This test is used to monitor treatment in someone who has been diagnosed with diabetes. It helps to evaluate how well their glucose levels have been controlled by treatment over time. This test may be used to screen for and diagnose diabetes or risk of developing diabetes. In 2010, clinical practice guidelines from the American Diabetes Association (ADA) stated that A1c may be added to fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) as an option for diabetes screening and diagnosis. For monitoring purposes, an A1c of less than 7% indicates good glucose control and a lower risk of diabetic complications for the majority of diabetics. However, in 2012, the ADA and the European Association for the Study of Diabetes (EASD) issued a position statement recommending that the management of glucose control in type 2 diabetes be more "patient-centered." Data from recent studies have shown that low blood sugar (hypoglycemia) can cause complications and that people with risk of severe hypoglycemia, underlying health conditions, complications, and a limited life expectancy do not necessarily benefit from having a stringent goal of less than 7% for their A1c. The statement recommends that people work closely with their doctor to select a goal that reflects each person's individual health status and that balances risks and benefits.

IA-2 ANTIBODY

Also known as: Insulin Response to Glucose 4 Specimens

Insulin, Specimen 1

Insulin, Specimen 2

Insulin, Specimen 3

Insulin, Specimen 4

Proinsulin

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The Advanced Blood Sugar Monitoring - Comprehensive panel contains 7 tests with 17 biomarkers.

Brief Description: The Advanced Blood Sugar Monitoring - Comprehensive panel is the most extensive assessment in the series, designed to provide a detailed analysis of glucose metabolism, insulin sensitivity, and autoimmune diabetes indicators. It includes Adiponectin, a 5 Specimens Glucose Tolerance Test, Glutamic Acid Decarboxylase-65 Antibody, Hemoglobin A1c, IA-2 Antibody, a 4 Specimens Insulin Response to Glucose, and Proinsulin tests.

Collection Method: Blood Draw

Specimen Type: Whole Blood, Plasma, and Serum

Test Preparation: Overnight fasting required. No food or beverage other than water for at least 8 hours before specimen collection.

High carbohydrate diet for 3 days before specimen collection

When and Why the Advanced Blood Sugar Monitoring - Comprehensive Panel May Be Ordered

This panel is often ordered for individuals who require a thorough assessment of their blood sugar regulation and insulin function, particularly if there is a suspicion of autoimmune diabetes or complex issues with glucose metabolism. It's also ideal for those with a family history of diabetes or those who have had inconclusive results from less extensive testing.

What the Advanced Blood Sugar Monitoring - Comprehensive Panel Checks For

  • Adiponectin: Evaluates a hormone that plays a role in regulating glucose levels and fatty acid breakdown, with implications for insulin sensitivity.

  • 5 Specimens Glucose Tolerance Test: Offers a comprehensive assessment of how the body processes glucose over time, providing insights into glucose tolerance and potential diabetes.

  • Glutamic Acid Decarboxylase-65 Antibody and IA-2 Antibody: Test for specific antibodies related to autoimmune diabetes, helping to distinguish Type 1 diabetes from other forms.

  • Hemoglobin A1c: Measures the average blood glucose levels over the past 2-3 months, indicating long-term glucose control.

  • 4 Specimens Insulin Response to Glucose: Assesses the body's insulin production in response to glucose intake, essential for evaluating insulin resistance and pancreatic function.

  • Proinsulin: Measures levels of proinsulin, an insulin precursor, which can provide insights into beta-cell function and the risk of developing diabetes.

Conditions or Diseases the Advanced Blood Sugar Monitoring - Comprehensive Panel Can Check For

This panel is crucial for diagnosing and managing diabetes, particularly in distinguishing Type 1 from Type 2 diabetes. It's also valuable for assessing insulin resistance, prediabetes, and for evaluating the risk of developing diabetes based on autoimmune markers and insulin production.

Use of Advanced Blood Sugar Monitoring - Comprehensive Panel Results by Healthcare Professionals

Healthcare professionals use the results to provide a comprehensive diabetes diagnosis, differentiate between autoimmune and non-autoimmune diabetes, assess glucose tolerance, and tailor treatment plans for diabetes management, including lifestyle and medication adjustments.

The Advanced Blood Sugar Monitoring - Comprehensive panel offers the most in-depth analysis available for assessing diabetes risk, insulin sensitivity, and autoimmune diabetes markers. It provides healthcare professionals with the detailed information needed to make accurate diagnoses and to manage diabetes effectively, ensuring personalized and effective treatment plans for individuals with complex or uncertain glucose metabolism issues.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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