The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: Apolipoprotein B Cardio IQ, Cardio IQ Apolipoprotein B
Also known as: Cardio IQ hs-CRP , hsCRP Cardio IQ
Also known as: Cardio IQ Lipid Panel, Lipid Panel Cardio IQ, Lipids
Also known as: Cardio IQ Lipoprotein (a), Lipoprotein a Cardio IQ
Also known as: Ion Mobility, Cardio IQ Lipoprotein Fractionation, Ion Mobility , HDL Subfractions, IDL Subfractions, LDL Subfractions, Lipoprotein Fraction, Lipoprotein Fractionation, Lipoprotein Fractionation Ion Mobility Cardio IQ, Quest Diagnostics has replaced the VAP® Cholesterol Test with Lipoprotein Fractionation, Ion Mobility, Cardio IQ™ test
The Advanced Cholesterol Panel + Inflammatory Marker panel contains 5 tests with 15 biomarkers.
Brief Description: The Advanced Cholesterol Panel + Inflammatory Marker Panel is a sophisticated diagnostic tool designed to evaluate cardiovascular risk from multiple dimensions. This comprehensive assessment combines traditional lipid profiling with advanced biomarkers for atherosclerosis and inflammation, offering a deep dive into an individual’s lipid metabolism and cardiovascular health. The integration of these tests provides a nuanced view of both the quantity and quality of cholesterol particles and the presence of inflammation, which is a known risk factor for cardiovascular diseases.
Collection Method: Blood Draw
Specimen Type: Serum
Test Preparation: Fasting for at least 12 hours is required.
This panel is typically ordered for individuals at moderate to high risk of cardiovascular disease, including those with a family history of heart disease, existing heart disease, diabetes, or hypertension. It is also recommended for those who may not have apparent risk factors but whose lifestyle—such as poor diet, physical inactivity, or smoking—might contribute to increased cardiovascular risk. The panel is crucial for guiding interventions and monitoring the effectiveness of treatments aimed at reducing cardiovascular risk.
Each component of the panel provides critical information on cardiovascular health risks:
Apolipoprotein B: This test measures the level of apolipoprotein B, a primary protein found in low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL). High levels are directly associated with a greater risk of cardiovascular disease as ApoB particles are the ones most likely to contribute to plaque formation in the arteries.
High Sensitivity C-Reactive Protein (hs-CRP): hs-CRP is a test that measures low levels of inflammation in the body. Chronic inflammation is linked to an increased risk of heart disease, and this test can be a predictor of future cardiovascular events.
Lipid Panel: This comprehensive test measures total cholesterol, high-density lipoprotein (HDL) cholesterol, LDL cholesterol, and triglycerides. It provides a baseline for understanding an individual’s risk of developing heart disease.
Lipoprotein (a): This test measures the level of lipoprotein (a), a particle that carries cholesterol and is similar to LDL. Elevated levels are considered a genetic risk factor for atherosclerosis.
Ion Mobility Lipoprotein Fractionation: This advanced test separates lipoprotein particles into subgroups by size and density. It allows for a more precise analysis of lipid risk factors, particularly identifying small, dense LDL particles that are more atherogenic.
The panel aids in the detection and management of several cardiovascular conditions:
Coronary Heart Disease: Elevated ApoB, high levels of small, dense LDL particles, and a high hs-CRP level are significant markers for coronary artery disease, indicating increased risk of clogged arteries.
Stroke: Elevated Lipoprotein (a) and inflammatory markers like hs-CRP can indicate an increased risk of stroke due to atherosclerosis and vascular inflammation.
Peripheral Artery Disease: Similar to coronary heart disease, the imbalance in lipid profiles, especially high levels of ApoB and low HDL, can predict peripheral artery disease.
Healthcare professionals use the results from this panel to:
Refine Risk Assessment: By understanding the detailed lipid profile and inflammatory status, clinicians can better estimate the cardiovascular risk, which is crucial for preventive strategies.
Tailor Treatment Approaches: Results can guide the prescription of statins, lifestyle changes, or other interventions based on specific lipid abnormalities or inflammation levels.
Monitor Treatment Efficacy: Ongoing assessments with the panel help evaluate the success of lifestyle changes or medications in altering lipid profiles and reducing inflammation.
The Advanced Cholesterol Panel + Inflammatory Marker Panel is an invaluable tool in modern preventive cardiology. It goes beyond traditional cholesterol testing by providing detailed insights into lipid particle behavior and inflammatory status, thus offering a more comprehensive assessment of cardiovascular risk. This enhanced understanding allows for more targeted interventions and personalized treatment plans, ultimately aiming to reduce the incidence and severity of cardiovascular disease.
We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.