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Also known as: Aspirin Resistance 11Dehydrothromboxane B2
The Aspirin Resistance (11-Dehydrothromboxane B2) test contains 1 test with 3 biomarkers.
Aspirin (which inhibits platelet cyclo-oxygenase) reduces the risk of thrombosis in cardiovascular disease by impairing platelet function. Patients who do not respond to the platelet inhibitory effects of aspirin are designated as "ASPIRIN RESISTANT". The measurement of 11-DEHYDROTHROMBOXANE B2 in urine (the principal metabolite of platelet cyclo-oxygenase derived thromboxane B2) indicates lack of aspirin responsiveness.