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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Creat

Creatinine

The creatinine blood test measures the level of creatinine in the blood. This test is done to see how well your kidneys work.

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Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.

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Glomerular filtration rate (GFR) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. Glomeruli are the tiny filters in the kidneys that filter waste from the blood.
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The Creatinine test contains 1 test with 3 biomarkers.

Brief Description: The Creatinine test is a common blood test used to measure the level of creatinine in the blood. Creatinine is a waste product generated from the breakdown of creatine, a molecule found in muscles. This test provides valuable information about kidney function and is essential in assessing and monitoring kidney health.

Also Known As: Create Test, Blood Creatinine Test, Serum Creatinine Test

Collection Method: Blood Draw

Specimen Type: Serum

Test Preparation: No preparation required

When is a Creatinine test ordered?

A healthcare provider may order a Creatinine test for various reasons, including:

  1. Kidney Function Evaluation: The test is primarily ordered as part of routine health check-ups or when there is a suspicion of kidney dysfunction. It helps assess the glomerular filtration rate (GFR), which is a key indicator of how well the kidneys are filtering waste from the blood.

  2. Monitoring Chronic Kidney Disease (CKD): For individuals with known kidney disease or conditions like diabetes or high blood pressure that can affect kidney function, regular Creatinine testing is essential for monitoring the progression of CKD.

  3. Medication Management: Certain medications, especially those excreted by the kidneys, may require dosing adjustments based on a patient's kidney function. Creatinine testing aids healthcare providers in determining appropriate drug doses.

  4. Preoperative Assessment: Before undergoing surgery, a Creatinine test may be performed to ensure the kidneys can handle the anesthesia and potential medications used during the procedure.

What does a Creatinine blood test check for?

Creatinine is a waste product created by muscles when a molecule called creatine is broken down. The kidneys eliminate creatinine from the body by filtering almost all of it from the blood and excreting it in the urine. The level of creatinine in the blood and/or urine is measured in this test.

Creatine is a component of the energy-producing cycle that allows muscles to contract. The body produces both creatine and creatinine at a roughly steady rate. Because the kidneys filter almost all creatinine from the blood and excrete it in the urine, blood levels are usually an excellent predictor of how well the kidneys are operating. The amount produced is determined by the person's size and muscular mass. As a result, men's creatinine levels will be slightly higher than women's and children's.

A blood creatinine test's results can be combined with those from other tests, such as a 24-hour urine creatinine test, to produce calculations that are used to assess kidney function.

Lab tests often ordered with a Creatinine test:

When a Creatinine test is ordered, it's often part of a broader evaluation of kidney health and function. Here are some tests commonly ordered alongside it:

  1. Blood Urea Nitrogen (BUN):

    • Purpose: To measure the amount of urea nitrogen in the blood, another waste product filtered by the kidneys.
    • Why Is It Ordered: BUN, when considered in conjunction with creatinine, can provide more insight into kidney function. An elevated BUN-to-creatinine ratio can suggest causes other than kidney damage, such as dehydration or gastrointestinal bleeding.
  2. Urinalysis:

    • Purpose: To analyze various components of the urine.
    • Why Is It Ordered: To check for abnormalities like protein, blood, or specific types of cells or casts that can indicate kidney disease.
  3. Urine Albumin (Microalbumin) and Albumin-to-Creatinine Ratio:

    • Purpose: To detect small amounts of albumin in the urine, an early sign of kidney damage.
    • Why Is It Ordered: To evaluate for early signs of kidney damage, particularly in people with risk factors like diabetes and hypertension.
  4. Complete Blood Count (CBC):

    • Purpose: To provide a broad picture of overall blood health, including red and white blood cells, and platelets.
    • Why Is It Ordered: To check for anemia or signs of infection, which can accompany kidney disease.
  5. Electrolyte Panel:

    • Purpose: To measure key electrolytes in the blood.
    • Why Is It Ordered: To assess electrolyte balance, which can be affected by kidney function.
  6. Phosphorus and Calcium Levels:

    • Purpose: To measure the levels of phosphorus and calcium in the blood.
    • Why Is It Ordered: Kidney dysfunction can lead to imbalances in phosphorus and calcium metabolism.
  7. Liver Function Test:

    • Purpose: To assess liver health.
    • Why Is It Ordered: To rule out liver conditions, as liver diseases can sometimes influence kidney function or the interpretation of certain test results.

These tests, when ordered alongside a Creatinine test, provide a comprehensive view of kidney function and overall health. They are crucial for diagnosing and managing kidney disease, monitoring the progression of chronic kidney conditions, and assessing the impact of various disorders on kidney health. The specific combination of tests will depend on the individual’s risk factors, symptoms, and underlying health conditions.

Conditions where a Creatinine test is recommended:

A Creatinine test is valuable in assessing and monitoring various kidney-related conditions, including:

  1. Chronic Kidney Disease (CKD): This test is essential for diagnosing and monitoring CKD, which can be caused by diabetes, high blood pressure, or other kidney disorders.

  2. Acute Kidney Injury (AKI): In cases of sudden kidney damage, the Creatinine test helps determine the severity and guide appropriate treatment.

  3. Kidney Infections: Elevated Creatinine levels may indicate kidney infections or other conditions affecting kidney function.

How does my health care provider use a Creatinine test?

Kidney function is assessed with a creatinine blood test. It's usually requested in conjunction with a BUN test or as part of a basic or comprehensive metabolic panel, which consists of a series of tests designed to assess the operation of the body's primary organs. BMP or CMP tests are used to screen healthy persons during normal physical exams, as well as to help evaluate people who are acutely or chronically ill in the emergency room and/or hospital. Creatinine testing is sometimes done as part of a renal panel to assess kidney function.

Creatinine is a waste product created by muscles when a molecule called creatine is broken down. Because the kidneys filter almost all creatinine from the blood and discharge it into the urine, blood levels are usually an excellent predictor of how well the kidneys are operating.

The kidneys are a pair of bean-shaped organs placed on the right and left sides of the back at the bottom of the ribcage. Nephrons are a million microscopic blood filtering units found within them. Blood is continuously filtered by a small cluster of looping blood arteries called a glomerulus in each nephron. Water and tiny molecules flow through the glomerulus, but blood cells and bigger molecules are retained. Each glomerulus has a little tube attached to it that gathers the fluid and molecules that flow through it and then reabsorbs what the body can use. Urine is formed from the residual waste.

If the creatinine and BUN tests are abnormal, or if the patient has an underlying condition that affects the kidneys, such as diabetes or high blood pressure, creatinine and BUN tests may be used to monitor renal functionality and therapy effectiveness. Before some procedures, such as a CT scan, that may necessitate the use of medicines that can harm the kidneys, blood creatinine and BUN tests may be requested to assess renal function.

Creatinine test results can be utilized in calculations to determine renal function.

The estimated glomerular filtration rate, used as a screen to search for signs of early kidney damage, is calculated using blood creatinine readings, as well as age, weight, and sex.

What do my Creatinine test results mean?

Elevated creatinine levels in the blood indicate renal disease or other disorders affecting kidney function.

Most Common Questions About the Creatinine test:

Understanding the Creatinine Test

What is the Creatinine test?

The Creatinine test is a blood test that measures the level of creatinine in your blood. Creatinine is a waste product that's produced by your muscles and filtered out of your body by your kidneys. The test helps evaluate how well your kidneys are working.

Why is the Creatinine test ordered?

The Creatinine test is often ordered to assess kidney function. It can be used to diagnose kidney disease, monitor the progress of known kidney disease, and evaluate the effectiveness of treatment for kidney disease.

How does the Creatinine test contribute to understanding my overall health?

The Creatinine test gives an indication of your kidney health. Since kidneys filter waste from the blood, high levels of creatinine can suggest that your kidneys aren't functioning properly. Conversely, normal levels suggest healthy kidney function.

Interpreting Creatinine Test Results

What does a high creatinine level indicate in the Creatinine test?

A high creatinine level in the Creatinine test often indicates impaired kidney function. This could be due to chronic kidney disease, acute kidney injury, dehydration, certain medications, or blockage in the urinary tract, among other conditions.

What does a low creatinine level indicate in the Creatinine test?

Low creatinine levels can be normal and are not usually a cause for concern. However, in some cases, they may suggest a lower than normal muscle mass due to conditions such as muscular dystrophy or severe liver disease.

What is considered a normal creatinine level in the Creatinine test?

Normal creatinine levels can vary based on age, race, gender, and body size. However, in general, normal blood creatinine levels range from about 0.6 to 1.3 milligrams per deciliter (mg/dL) in adult males and 0.5 to 1.03 mg/dL in adult females.

Creatinine Test and Specific Health Conditions

How is the Creatinine test used in diagnosing kidney diseases?

The Creatinine test is one of the most commonly used tests to assess kidney function. High levels of creatinine can indicate that the kidneys are not effectively filtering waste products from the blood, which can be a sign of kidney disease.

How does the Creatinine test help in managing diabetes or hypertension?

For people with diabetes or hypertension, both conditions that can damage kidneys over time, regular creatinine testing can help monitor kidney function and determine if treatment adjustments are needed to better protect the kidneys.

Can the Creatinine test be used to diagnose other health conditions?

While the primary use of the Creatinine test is to evaluate kidney function, it can also aid in diagnosing conditions that can affect the kidneys such as severe infections, certain autoimmune diseases, or severe heart failure.

Creatinine Test and Treatment Monitoring

How is the Creatinine test used to monitor treatment effectiveness?

For patients with kidney disease, the Creatinine test is used to monitor the effectiveness of treatments. If creatinine levels decrease over time, it's generally a sign that treatments are helping and kidney function is improving.

How frequently should the Creatinine test be repeated?

The frequency of Creatinine testing depends on the patient's health status. For those with kidney disease, diabetes, or hypertension, regular testing is typically recommended. However, the specific frequency should be determined by a healthcare provider.

Clinical Guidelines and Recommendations

What are the guidelines for using the Creatinine test in clinical practice?

The Creatinine test is recommended for use in routine medical exams, especially for those with risk factors for kidney disease such as diabetes or hypertension. It's also recommended for monitoring those with known kidney disease or as part of the diagnostic process if kidney disease is suspected.

Can the Creatinine test be used in preventive health check-ups?

Yes, the Creatinine test is often included in routine health check-ups to evaluate kidney function, especially for people with risk factors for kidney disease.

Creatinine Test and Other Diagnostic Tools

What is the difference between the Creatinine test and the Blood Urea Nitrogen (BUN) test?

While both tests assess kidney function, they measure different waste products in your blood. The BUN test measures the amount of urea nitrogen, another waste product that's filtered out by the kidneys. Together with the Creatinine test, the BUN test can provide a more comprehensive view of kidney function.

How does the Creatinine test relate to the Glomerular Filtration Rate (GFR)?

The Glomerular Filtration Rate (GFR) is a calculation that's often done using the results from the Creatinine test. It provides the best overall assessment of kidney function by estimating how much blood passes through the glomeruli (tiny filters in the kidneys) each minute.

What other tests might be done alongside the Creatinine test?

Other tests that might be done alongside the Creatinine test include the BUN test, urine creatinine test, or a complete blood count. These tests can provide additional information about kidney function and overall health.

Patient Considerations

What should I do if my creatinine levels are high in the Creatinine test?

If your creatinine levels are high, it's important to talk with your healthcare provider about what this might mean for your health. They may recommend additional testing or changes in your treatment plan.

Are there any lifestyle changes that can affect my creatinine levels?

Yes, certain lifestyle changes can help improve kidney function and thus lower creatinine levels. These can include staying hydrated, maintaining a healthy weight, exercising regularly, and managing conditions such as diabetes or hypertension.

Can certain foods or medications affect my creatinine levels?

Yes, certain medications can increase creatinine levels, including some antibiotics and medications for hypertension. In terms of diet, consuming large amounts of protein can also temporarily raise creatinine levels.

How does aging affect the results of the Creatinine test?

As you age, you may lose muscle mass, which can lead to lower creatinine levels. Also, kidney function generally decreases with age, which could lead to higher creatinine levels.

What does the Creatinine test mean for my long-term health?

The Creatinine test is a key indicator of kidney health. Chronic high creatinine levels could indicate a long-term issue with kidney function, which can have serious health implications if not addressed.

How should I interpret my Creatinine test results in the context of my overall health?

Creatinine test results should be interpreted in the context of your overall health and any symptoms you're experiencing. High creatinine levels, particularly if they persist over time, could be a sign of kidney disease, but they can also be influenced by other factors such as medications or diet.

Are there any alternatives to the Creatinine test?

While the Creatinine test is a standard measure of kidney function, it's often used in combination with other tests such as the BUN test or urine tests to give a fuller picture of kidney health.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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