Depression Nutrient Deficiency Panel

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Chromium Blood

Chromium, Blood

Also known as: Iron Total

Iron, Total

Iron is a mineral that our bodies need for many functions. For example, iron is part of hemoglobin, a protein which carries oxygen from our lungs throughout our bodies. It helps our muscles store and use oxygen. Iron is also part of many other proteins and enzymes. Your body needs the right amount of iron. If you have too little iron, you may develop iron deficiency anemia. Causes of low iron levels include blood loss, poor diet, or an inability to absorb enough iron from foods. People at higher risk of having too little iron are young children and women who are pregnant or have periods.

Magnesium

Selenium

Also known as: B1, B1 Vitamin, Thiamine, Vitamin B1, Vitamin B1 Thiamine LCMSMS

Vitamin B1 (Thiamine),

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Factor X Activity,

Vitamin B6

Also known as: Alpha-Tocopherol, Vitamin E Tocopherol

Alpha-Tocopherol

Beta-Gamma-Tocopherol

Also known as: ZN, Plasma

Zinc

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The Depression Nutrient Deficiency Panel panel contains 9 tests with 12 biomarkers.

The Depression Nutrient Deficiency Panel is a comprehensive diagnostic tool designed to evaluate specific nutrient levels in the body that are crucial for mental health and cognitive function. This panel assesses a range of vitamins and minerals that have been linked to depression and other mood disorders. By identifying deficiencies in these essential nutrients, healthcare providers can better understand the underlying biochemical factors contributing to a patient's depressive symptoms and tailor appropriate nutritional and therapeutic interventions.

When and Why the Depression Nutrient Deficiency Panel May Be Ordered

This panel may be ordered when a patient presents with symptoms of depression or other mood disorders, and there is a suspicion that nutritional deficiencies might be contributing to these mental health issues. It is particularly useful for patients who have not responded well to traditional antidepressant therapies, those with dietary restrictions, or individuals with conditions that may impair nutrient absorption. Additionally, it can be ordered as part of a comprehensive assessment in patients with chronic fatigue, cognitive decline, or other neurological symptoms.

What the Depression Nutrient Deficiency Panel Checks For

The Depression Nutrient Deficiency Panel includes tests that measure levels of essential vitamins and minerals, each playing a unique role in mental health:

  • Vitamin B1 (Thiamine): Thiamine is crucial for energy metabolism and neurological function. Deficiency can lead to symptoms such as irritability, depression, and cognitive decline.
  • Vitamin B6 (Pyridoxine): Pyridoxine is essential for neurotransmitter synthesis, including serotonin and dopamine, which regulate mood. Deficiency can result in mood disturbances and cognitive issues.
  • Vitamin B9 (Folate): Folate is vital for DNA synthesis and repair, as well as neurotransmitter production. Deficiency is linked to depression and cognitive impairment.
  • Vitamin B12 (Cobalamin): Cobalamin is critical for neurological function and the production of red blood cells. Deficiency can lead to severe depression, fatigue, and memory issues.
  • Vitamin E: An antioxidant that protects cells from oxidative stress. Deficiency may contribute to neurodegeneration and mood disorders.
  • Chromium: Chromium is involved in regulating blood sugar levels and may influence mood by modulating insulin and glucose metabolism.
  • Iron: Iron is essential for oxygen transport and energy production. Deficiency can lead to fatigue, cognitive decline, and depression.
  • Magnesium: Magnesium plays a role in over 300 enzymatic reactions, including those involved in mood regulation and neurological function. Deficiency is associated with anxiety and depression.
  • Selenium: Selenium is important for antioxidant defense and thyroid function. Low levels can impact mood and cognitive function.
  • Zinc: Zinc is crucial for brain function and the immune system. Deficiency has been linked to mood disorders and cognitive dysfunction.

Conditions or Diseases the Depression Nutrient Deficiency Panel Can Detect

The Depression Nutrient Deficiency Panel can detect several conditions that may contribute to depression and other mental health issues:

  • Depression: A mood disorder characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. Nutrient deficiencies can exacerbate or even cause depressive symptoms. For instance, low levels of vitamins B6, B12, and folate are directly linked to mood disturbances.
  • Cognitive Decline: A broad term that encompasses various symptoms related to memory loss, diminished problem-solving skills, and decreased ability to perform everyday tasks. Deficiencies in vitamins B1, B6, B12, folate, and magnesium can significantly impact cognitive function.
  • Chronic Fatigue Syndrome: A complex disorder characterized by extreme fatigue that cannot be explained by an underlying medical condition. Deficiencies in iron, magnesium, and other nutrients can contribute to the persistent fatigue experienced in this condition.
  • Neurological Disorders: Conditions such as peripheral neuropathy, where nutrient deficiencies (particularly vitamins B1, B6, and B12) play a significant role in the development and progression of neurological symptoms.

How a Healthcare Professional Would Use the Results of the Depression Nutrient Deficiency Panel

Healthcare professionals use the results of the Depression Nutrient Deficiency Panel to guide the diagnosis and management of various conditions:

  • Depression: If nutrient deficiencies are identified, the healthcare provider can recommend dietary modifications, supplements, or both to address these deficiencies. For example, increasing the intake of vitamin B12 and folate-rich foods or prescribing supplements can help alleviate depressive symptoms.
  • Cognitive Decline: Addressing deficiencies in vitamins B1, B6, B12, folate, and magnesium can help improve cognitive function and slow the progression of cognitive decline. This might involve nutritional counseling and supplementation.
  • Chronic Fatigue Syndrome: Identifying and correcting deficiencies in iron, magnesium, and other essential nutrients can help reduce fatigue and improve overall energy levels. Treatment plans may include iron supplements, magnesium-rich foods, or specific dietary adjustments.
  • Neurological Disorders: For conditions like peripheral neuropathy, supplementing with deficient nutrients, particularly vitamins B1, B6, and B12, can help reduce symptoms and prevent further neurological damage. A comprehensive approach may include both dietary changes and targeted supplementation.

The Depression Nutrient Deficiency Panel is a valuable tool for identifying nutrient deficiencies that can contribute to depression and other mental health issues. By assessing levels of essential vitamins and minerals, healthcare providers can develop personalized treatment plans to address these deficiencies, improve mental health outcomes, and enhance overall well-being. Whether for diagnosing conditions like depression and cognitive decline or for managing chronic fatigue and neurological disorders, this panel provides critical insights that support effective and holistic patient care.

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