Drug Monitoring, Amphetamines, with D/L, Quantitative, Urine

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Amphetamine

Medmatch Amphetamine

Methamphetamine

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The Drug Monitoring, Amphetamines, with D/L, Quantitative, Urine test contains 1 test with 3 biomarkers.

Drug Monitoring, Amphetamines, with D/L, Quantitative, Urine

Clinical Significance
Drug Monitoring, Amphetamines, with D/L, Quantitative, Urine - Methamphetamine has two isomers, d-methamphetamine (dextromethamphetamine) and l-methamphetamine (levomethamphetamine). d-methamphetamine is most often illicitly manufactured and is considered a drug of abuse (Crystal meth, etc.). It is approved as a treatment for ADHD and obesity, although its use is very limited. l-methamphetamine is used in certain nonprescription inhalers as a decongestant. This test is a definitive assay using a gas chromatography mass spectroscopy (GC-MS) method of analysis. In routine confirmation testing of amphetamines, the specific methamphetamine isomers are not differentiated, and reported as "Methamphetamine". In situations where this is an unexpected result, it may be useful to determine the relative percentages of each isomer present. The presence of the l-isomer at greater than 80% is consistent with the use of non-prescription inhalers. The presence of the d-isomer greater than 20% is consistent with the use of prescribed medication or illegally manufactured methamphetamine. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Amphetamine and Methamphetamine
If the Methamphetamine is reported Positive (≥250 ng/mL), Pain Management, Methamphetamine, D/L Isomers, Urine will be performed at an additional charge (CPT code(s): 80374 HCPCS: G0480)

Reference Range(s)
Amphetamine    <250 ng/mL
Methamphetamine    <250 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

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