Drug Monitoring, Propoxyphene Metabolite, Quantitative, Urine

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Medmatch Norpropoxyphene

Norpropoxyphene

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The Drug Monitoring, Propoxyphene Metabolite, Quantitative, Urine test contains 1 test with 2 biomarkers.

Drug Monitoring, Propoxyphene Metabolite, Quantitative, Urine

Clinical Significance
Drug Monitoring, Propoxyphene Metabolite, Quantitative, Urine - d-Propoxyphene is a narcotic analgesic that is structurally related to methadone. The l-isomer is devoid of narcotic effects and is available as an antitussive. The FDA mandated the removal of propoxyphene products used for pain management in 2010. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of propoxyphene is important for ensuring compliance to treatment strategies. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.

Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
 
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
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Norpropoxyphene

Reference Range(s)
Norpropoxyphene    <200 ng/mL

Alternative Name(s)
Prescription Drug Monitoring,Pain Management

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