The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
The Drug Monitoring, Tricyclic Antidepressants, Quantitative, Urine test contains 1 test with 3 biomarkers.
Drug Monitoring, Tricyclic Antidepressants, Quantitative, Urine
Clinical Significance
Drug Monitoring, Tricyclic Antidepressants, Quantitative, Urine - Amitriptyline and nortriptyline are used to treat various forms of depression and chronic neuropathic pain. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of these drugs is important for ensuring compliance to treatment strategies. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.
Includes
If you require medMATCH for this order code, you must also order code 39158 - Prescribed Drugs, medMATCH®. If 39158 is ordered, all Drug Monitoring order codes will be treated as medMATCH.
If this test code is not ordered with 39158, all medMATCH result codes will be DNR’d.
.
Amitriptyline and Nortriptyline
Reference Range(s)
Amitriptyline <100 ng/mL
Nortriptyline <100 ng/mL
Alternative Name(s)
Prescription Drug Monitoring,Pain Management