Estrogens, Fractionated, LC/MS

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Estrogens Fractionated LCMSMS

Estradiol, Ultrasensitive

Estriol, LC/MS/MS, Serum

Estrone, LC/MS/MS

Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Individuals with obesity have increased conversion of androstenedione to Estrone leading to higher concentrations. In addition, an increase in the ratio of Estrone to Estradiol may be useful in assessing menopause in women. Estrone levels may be elevated in patients with polycystic ovarian syndrome and endometriosis. Tests may be used to aid in the diagnosis of an ovarian tumor, Turner syndrome, and hypopituitarism. In males, it may help in the diagnosis of the cause of gynecomastia or in the detection of estrogen-producing tumors.
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The Estrogens, Fractionated, LC/MS test contains 1 test with 3 biomarkers.

Estrogens, Fractionated, LC/MS includes the following tests.

  • Estrone
  • Estradiol, Ultrasensitive, LC/MS
  • Estriol, Serum

Note: Norethindrone acetate/Norethisterone acetate is known to interfere with the measurement of estrone using the Quest Diagnostics LC-MS/MS method. This test should not be used to quantitate estrone in patients taking this drug.

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