HDL Function Panel with HDLfx pCAD Score

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

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The HDL Function Panel with HDLfx pCAD Score test contains 1 test.

The HDL Function Panel with HDLfx pCAD Score is a comprehensive blood test designed to assess the functional aspects of High-Density Lipoprotein (HDL), often referred to as "good cholesterol." This panel evaluates the efficiency of HDL in protecting against the development of premature coronary artery disease (pCAD). By examining specific apolipoproteins and generating an HDLfx pCAD Score, this test offers a nuanced view of cardiovascular health beyond traditional cholesterol testing.

Test Components:

  1. AALP Apolipoprotein A1: Measures the levels of Apolipoprotein A1, a major component of HDL particles, essential for the activation of the enzyme that helps remove excess cholesterol from cells and tissues.

  2. AALP Apolipoprotein C1: Apolipoprotein C1 plays a role in modulating lipoprotein metabolism and helps in the regulation of HDL's protective effects against cardiovascular disease.

  3. AALP Apolipoprotein C2: This apolipoprotein is crucial for the activation of lipoprotein lipase, an enzyme involved in the breakdown of fats. Apolipoprotein C2 levels can influence HDL functionality and overall lipid metabolism.

  4. AALP Apolipoprotein C3: Apolipoprotein C3 can inhibit lipoprotein lipase and is involved in the regulation of triglyceride metabolism, affecting HDL's efficiency in transporting cholesterol.

  5. AALP Apolipoprotein C4: Although less studied, Apolipoprotein C4 is believed to play a role in lipid metabolism and potentially impact HDL function and cardiovascular risk.

  6. HDLfx pCAD Score: This score integrates the levels and functionalities of various HDL-associated apolipoproteins to predict the risk of developing premature coronary artery disease. It provides a personalized risk assessment, helping to guide preventive and therapeutic strategies.

Importance:

Traditional lipid profiles provide a broad overview of cardiovascular risk based on cholesterol levels. However, the HDL Function Panel with HDLfx pCAD Score delves deeper, offering insights into the protective mechanisms of HDL cholesterol. Understanding the functionality of HDL and its components can lead to more targeted interventions for improving heart health and reducing the risk of heart disease.

Ideal For:

This panel is particularly beneficial for individuals with known risk factors for heart disease, those with a family history of cardiovascular issues, or anyone seeking a detailed analysis of their heart health. It can also be invaluable for tailoring treatment strategies in patients with existing heart conditions or those looking to optimize their cardiovascular health proactively.

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