The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
The Hepatitis C Antibody with Reflex to HCV RNA,PCR w/Reflex to Genotype, LiPA test contains 1 test with 2 biomarkers.
Clinical Significance
Hepatitis C Antibody with Reflex to HCV RNA,PCR w/Reflex to Genotype, LiPA - Hepatitis C Virus (HCV) is the major cause of hepatitis. Making positive HCV Ab tests reflex to confirmatory molecular testing is necessary to confirm active HCV infection. Providing a second reflex to perform genotyping on HCV isolates when RNA is detected is also a necessary step before starting therapy. This double reflex will reduce the percentage of antibody-positive patients who lack appropriate confirmatory RNA testing and who do not have genotype testing performed.
Important Reflex Note: If Hepatitis C Antibody is reactive or borderline, then Hepatitis C Viral RNA, Quantitative, Real-Time PCR will be performed at an additional charge. If Hepatitis C Viral RNA, Quantitative, Real-Time PCR is ≥300 IU/mL, then Hepatitis C Viral RNA Genotype, LiPA will be performed at an additional charge.