HSV 1/2 IgG, Herpeselect W/Refl HSV2 Inhibition

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Hsv 12 IgG Herpeselect WRefl Hsv2 Inhibition

Hsv 1 IgG Type Specific

Herpes simplex virus testing is performed to identify an acute herpes infection or to detect herpes antibodies, an indication of a previous exposure to herpes. One of the most common viral infections, herpes simplex virus (HSV) exists as two main types, HSV-1 and HSV-2. Both types are contagious and periodically cause small fever blisters (vesicles) that break to form open lesions. HSV-1 primarily causes blisters or "cold sores" around the oral cavity and mouth, while HSV-2 usually causes lesions around the genital area; however, either one can affect the oral or genital area.

Hsv 2 IgG Type Specific

Herpes simplex virus testing is performed to identify an acute herpes infection or to detect herpes antibodies, an indication of a previous exposure to herpes. One of the most common viral infections, herpes simplex virus (HSV) exists as two main types, HSV-1 and HSV-2. Both types are contagious and periodically cause small fever blisters (vesicles) that break to form open lesions. HSV-1 primarily causes blisters or "cold sores" around the oral cavity and mouth, while HSV-2 usually causes lesions around the genital area; however, either one can affect the oral or genital area.
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The HSV 1/2 IgG, Herpeselect W/Refl HSV2 Inhibition test contains 1 test with 2 biomarkers.

HSV 1/2 IgG, HerpeSelect w/Reflex to HSV-2 Inhibition Test Description

Herpes Simplex Virus (HSV) types 1 and 2 are pervasive pathogens responsible for a wide range of medical conditions, from mild oral and genital lesions to severe infections such as neonatal herpes and meningoencephalitis. Understanding which type of HSV a patient has contracted is crucial for effective management and treatment. The HSV 1/2 IgG, HerpeSelect with Reflex to HSV-2 Inhibition test provides a targeted approach to not only detect these viruses but also differentiate between the two types, offering critical insights into the appropriate therapeutic strategies.

Please note that the HSV 1/2 IgG, HerpeSelect test includes a reflex component. If the Herpes Simplex Virus 2 (IgG) level is greater than 1.09, an HSV-2 Inhibition Study will automatically be performed to confirm the results. Be aware that this additional test will incur extra charges. Please plan accordingly.

Test Components and Diagnostic Significance:

  • Herpes Simplex Virus 1/2 (IgG): This component of the panel tests for IgG antibodies to HSV-1 and HSV-2, indicating past or present infection.

    • Detection: Determines the presence of IgG antibodies that suggest historical or ongoing exposure to the viruses.
    • Diagnosis: By identifying the specific IgG antibodies, clinicians can ascertain whether the infection is oral or genital, facilitating targeted treatments.

  • HSV-2 Inhibition Study: Triggered if the HSV-2 IgG result is greater than 1.09. This test confirms whether a positive HSV-2 result is accurate by measuring the specific inhibition of glycoprotein G2, the antigen specific to HSV-2.

    • Detection: Enhances specificity by verifying that the antibodies are indeed reactive against HSV-2 and not cross-reactive from other conditions.
    • Diagnosis: Critical for confirming true HSV-2 status in patients, particularly in cases where initial results are ambiguous.

Methodology:

  • The tests employ an Immunoassay (IA) method that uses recombinant type-specific antigens to effectively differentiate between HSV-1 and HSV-2 infections, ensuring high specificity in the results.

Sample Ulta Lab Tests View of Herpes 1 and 2 Antibody Results

Sample Quest Result Report View of herpes 1 and 2 Antibody Results

Sample Results of Herpes 2 Antibody reflexing into Herpes 2 IgG Inhibition Test

Reference Ranges and Interpretations:

  • Negative: <0.90 – Indicates no significant levels of HSV-specific IgG detected.
  • Equivocal: 0.90-1.09 – Suggests uncertain HSV IgG presence; further testing recommended.
  • Positive: >1.09 – Significant levels of HSV-specific IgG detected; reflex inhibition study will be conducted if HSV-2 IgG is positive.

Symptoms of HSV to Recognize:

  • Oral Lesions: Cold sores or fever blisters around the mouth, commonly caused by HSV-1.
  • Genital Lesions: Painful blisters or ulcers in the genital area, typically associated with HSV-2.
  • Systemic Symptoms: Fever, body aches, and swollen lymph nodes can accompany initial or recurrent outbreaks.

Benefits of Using Ulta Lab Tests:

  • Convenience and Accessibility: Easily accessible testing that doesn’t necessarily require a physician's referral.
  • Quick and Reliable Results: Efficient processing with reliable results that help in swift medical decision-making.
  • Confidentiality Assured: Secure and private handling of all test results and patient information.
  • Cost-Effectiveness: Competitive pricing and the opportunity to save with ongoing promotions such as 20% off on specific tests.

The HSV 1/2 IgG, HerpeSelect with Reflex to HSV-2 Inhibition test from Ulta Lab Tests is an indispensable tool for anyone requiring definitive analysis of Herpes Simplex Virus exposure and type differentiation. With this test, patients and healthcare providers can gain crucial insights into the nature of the herpes infection, guiding more effective treatment and management strategies. Take advantage of Ulta Lab Tests’ special offerings and prioritize your health with accurate, reliable, and confidential testing.

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