The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
The Islet Cell Antibody Screen with Reflex to Titer test contains 1 test with 1 biomarker.
Islet Cell Antibody Screen with Reflex to Titer
If Islet Cell Antibody Screen is positive, then Islet Cell Antibody Titer will be performed at an additional charge
Reference Range(s)
Islet Cell Antibody ScreenNegative
Islet Cell Antibody Titer<1.25 JDF units
Clinical Significance
Islet Cell Antibody Screen with Reflex to Titer - Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type 1 diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.