Mental Wellness Insight: Blood Biomarker Analysis

The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Amino Acid Analysis LCMS Plasma

1-Methylhistidine

3-Methylhistidine

Alanine

Alpha Amino Adipic Acid

Alpha Amino Butyric Acid

Arginine

Asparagine

Aspartic Acid

Beta Amino Isobutyric

Beta-Alanine

Citrulline

Cystathionine

Date Of Birth

Ethanolamine

Gamma Amino Butyric Acid

Glutamic Acid

Glutamine

Glycine

Histidine

Homocystine

Hydroxyproline

Interpretation

Isoleucine

Leucine

Lysine

Methionine

Ornithine

Phenylalanine

Proline

Sarcosine

Serine

Taurine

Threonine

Tryptophan

Tyrosine

Valine

Also known as: CBC, CBC includes Differential and Platelets, CBC/PLT w/DIFF, Complete Blood Count (includes Differential and Platelets)

NOTE: Ulta Lab Tests provides CBC test results from Quest Diagnostics as they are reported. Often, different biomarker results are made available at different time intervals. When reporting the results, Ulta Lab Tests denotes those biomarkers not yet reported as 'pending' for every biomarker the test might report. Only biomarkers Quest Diagnostics observes are incorporated and represented in the final CBC test results provided by Ulta Lab Tests.

Absolute Band Neutrophils

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Absolute Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Absolute Blasts

Blasts are immature forms of white blood cells.

Absolute Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Absolute Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Absolute Metamyelocytes

Metamyelocytes are immature forms of white blood cells.

Absolute Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

Absolute Myelocytes

Myelocytes are immature forms of white blood cells.

Absolute Neutrophils

Neutrophils (neu) normally make up the largest number of circulating WBCs. They move into an area of damaged or infected tissue, where they engulf and destroy bacteria or sometimes fungi. Young neutrophils, recently released into circulation, are called bands.

Absolute Nucleated Rbc

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Absolute Promyelocytes

Promyelocytes are immature forms of white blood cells.

Band Neutrophils

Immature forms of neutrophils are called neutrophilic band cells. Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed. Large numbers of immature forms of neutrophils, called neutrophilic band cells, are produced by the bone marrow when the demand is high.

Basophils

Basophils normally constitute 1% or less of the total white blood cell count but may increase or decrease in certain diseases and are thought to be involved in allergic reactions.

Blasts

Blasts are immature forms of white blood cells.

Eosinophils

Eosinophils (eos) respond to infections caused by parasites and play a role in allergic reactions (hypersensitivities)

Hematocrit

Hematocrit is a blood test that measures the percentage of the volume of whole blood that is made up of red blood cells. This measurement depends on the number of red blood cells and the size of red blood cells.

Hemoglobin

Serum hemoglobin is a blood test that measures the level of free hemoglobin in the liquid part of the blood (the serum). Free hemoglobin is the hemoglobin outside of the red blood cells. Most of the hemoglobin is found inside the red blood cells, not in the serum.

Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

MCH

Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of oxygen-carrying hemoglobin inside a red blood cell.

MCHC

Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average percentage of hemoglobin inside a red cell.

MCV

Mean corpuscular volume (MCV) is a measurement of the average size of RBCs.

Metamyelocytes

Metamyelocytes are immature forms of white blood cells.

Monocytes

Monocytes (mono), similar to neutrophils, move to an area of infection and engulf and destroy bacteria. They are associated more often with chronic rather than acute infections. They are also involved in tissue repair and other functions involving the immune system.

MPV

Mean Platelet Volume (MPV) - When it indicates average size of platelets are small; older platelets are generally smaller than younger ones and a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. When it indicates a high number of larger, younger platelets in the blood; this may be due to the bone marrow producing and releasing platelets rapidly into circulation.

Myelocytes

Myelocytes are immature forms of white blood cells.

Neutrophils

Neutrophils are a type of white blood cell that is responsible for much of the body's protection against infection. Neutrophils are produced in the bone marrow and released into the bloodstream to travel to wherever they are needed.

Nucleated Rbc

Nucleated Red Blood Cells (nRBC) ) the presence of NRBCs in the adult blood is usually associated with malignant neoplasms, bone marrow diseases, and other serious disorders.

Platelet Count

A platelet count is a test to measure how many platelets you have in your blood. Platelets help the blood clot. They are smaller than red or white blood cells.

Promyelocytes

Promyelocytes are immature forms of white blood cells.

RDW

Red cell distribution width (RDW), which may be included in a CBC, is a calculation of the variation in the size of RBCs.

Reactive Lymphocytes

Lymphocytes are white blood cells that exist in both the blood and the lymphatic system. They are divided into three types. The B lymphocytes (B cells) are antibody-producing cells that are essential for acquired, antigen-specific immune responses. The second type are T lymphocytes (T cells) some T cells help the body distinguish between "self" and "non-self" antigens while others initiate and control the extent of an immune response, boosting it as needed and then slowing it as the condition resolves. Other types of T cells directly attack and neutralize virus-infected or cancerous cells. The third type are natural killer cells (NK cells) that directly attack and kill abnormal cells such as cancer cells or those infected with a virus.

Red Blood Cell Count

An RBC count is a blood test that tells how many red blood cells (RBCs) you have. RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

White Blood Cell Count

A WBC count is a test to measure the number of white blood cells (WBCs) in the blood. WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

Also known as: Cortisol Total, Hydrocortisone, Total Cortisol

Cortisol, Total

Also known as: Estrogen Total Serum

Estrogen, Total, Serum

Estrogen is a group of steroids that regulate the menstrual cycle and function as the main female sex hormones. Estrogens are responsible for the development of female sex organs and secondary sex characteristics and are tied to the menstrual cycle and pregnancy. They are considered the main sex hormones in women and are present in small quantities in men.

Magnesium

VITAMIN B1 (THIAMINE),

ARACHIDONIC ACID

ARACHIDONIC ACID/EPA

DHA

DPA

EPA

EPA+DPA+DHA

LINOLEIC ACID

OMEGA-3 TOTAL

OMEGA-6 TOTAL

OMEGA-6/OMEGA-3 RATIO

Also known as: Progesterone Immunoassay

Progesterone

Serum progesterone is a test to measure the amount of progesterone in the blood. Progesterone is a hormone produced mainly in the ovaries. In women, progesterone plays a vital role in pregnancy. After an egg is released by the ovaries (ovulation), progesterone helps make the uterus ready for implantation of a fertilized egg. It prepares the womb (uterus) for pregnancy and the breasts for milk production. Men produce some amount of progesterone, but it probably has no normal function except to help produce other steroid hormones.

Vitamin D, 25-Oh, D2

Vitamin D2 ((ergocalciferol,) is found in fortified foods and in most vitamin preparations and supplements. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D2 is effective when it is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, D3

Vitamin D3 (cholecalcifero) which comes from animals. Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D3 are is converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Vitamin D, 25-Oh, Total

Vitamin D comes from two sources: endogenous, which is produced in the skin on exposure to sunlight, and exogenous, which is ingested in foods and supplements. The chemical structures of the types of vitamin D are slightly different, and they are named vitamin D2 (ergocalciferol, which comes from plants) and vitamin D3 (cholecalciferol, which comes from animals). The D2 form is found in fortified foods and in most vitamin preparations and supplements. Vitamin D3 is the form produced in the body and is also used in some supplements. Vitamin D2 and D3 are equally effective when they are converted by the liver and the kidney into the active form, 1,25-dihydroxyvitamin D.

Also known as: Free T3, FT3, T3 Free

T3, Free

This test measures the amount of triiodothyronine, or T3, in the blood.

Also known as: Free T4, FT4, T4 Free

T4, Free

The free T4 test is not affected by protein levels. Since free T4 is the active form of thyroxine, the free T4 test is may be a more accurate reflection of thyroid hormone function.

Also known as: Testosterone Total And Free And Sex Hormone Binding Globulin

Free Testosterone

In many cases, measurement of total testosterone provides the doctor with adequate information. However, in certain cases, for example when the level of SHBG is abnormal, a test for free or bioavailable testosterone may be performed as it may more accurately reflect the presence of a medical condition.

Sex Hormone Binding

The sex hormone binding globulin (SHBG) test measures the concentration of SHBG in the blood. SHBG is a protein that is produced by the liver and binds tightly to testosterone, dihydrotestosterone (DHT), and estradiol (an estrogen). In this bound state, it transports them in the blood as an inactive form. The amount of SHBG in circulation is affected by age and sex, by decreased or increased testosterone or estrogen production and can be affected by certain diseases and conditions such as liver disease, hyperthyroidism or hypothyroidism, and obesity. Changes in SHBG levels can affect the amount of testosterone that is available to be used by the body's tissues. A total testosterone test does not distinguish between bound and unbound testosterone but determines the overall quantity of testosterone. If a person's SHBG level is not normal, then the total testosterone may not be an accurate representation of the amount of testosterone that is available to the person's tissues.

TESTOSTERONE, TOTAL,

A testosterone test measures the amount of the male hormone, testosterone, in the blood. Both men and women produce this hormone. In males, the testicles produce most of the testosterone in the body. Levels are most often checked to evaluate signs of low testosterone: In boys -- early or late puberty and in men -- impotence, low level of sexual interest, infertility, thinning of the bones In females, the ovaries produce most of the testosterone and levels are most often checked to evaluate signs of higher testosterone levels, such as: decreased breast size, excess hair growth, increased size of the clitoris. irregular or absent menstrual periods and male-pattern baldness or hair thinning.

Also known as: Thyroid Stimulating Hormone, Thyroid Stimulating Hormone (TSH), Thyrotropin

TSH

A TSH test is a lab test that measures the amount of thyroid stimulating hormone (TSH) in your blood. TSH is produced by the pituitary gland. It tells the thyroid gland to make and release thyroid hormones into the blood.

TSH

Also known as: Cobalamin, Folic Acid, Vitamin B 12, Vitamin B 12 and Folic Acid, Vitamin B12 Cobalamin and Folate Panel Serum, Vitamin B12/Folic Acid

Folate, Serum

Folate is part of the B complex of vitamins and is measures the levels of folate in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Folate is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis.. A deficiency inr folate can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow.

Vitamin B12

Vitamin B12 is part of the B complex of vitamins and measurea the levels of vitamin B12 in the liquid portion of the blood, the serum or plasma, to detect deficiencies. Cobalamine, or vitamin B12, is found in animal products such as red meat, fish, poultry, milk, yogurt, and eggs and is not produced in the human body. In recent years, fortified cereals, breads, and other grain products have also become important dietary sources of B12. Vitamin B12 is necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis. B12 is important for nerve health. A deficiency in B12 can lead to macrocytic anemia. Megaloblastic anemia, a type of macrocytic anemia, is characterized by the production of fewer but larger RBCs called macrocytes, in addition to some cellular changes in the bone marrow. B12 deficiency can lead to varying degrees of neuropathy, nerve damage that can cause tingling and numbness in the affected person's hands and feet.

Also known as: B2, Riboflavin, Vitamin B2, Vitamin B2 Riboflavin Plasma

Vitamin B2 (Riboflavin),

Also known as: B3, B3 Vitamin, Niacin, Nicotinamide, Nicotinic acid, Vitamin B3 Nicotinic acid

Nicotinamide

Nicotinic Acid

Also known as: B5 Vitamin, Pantothenic acid, Vitamin B5 Pantothenic Acid

Vitamin B5 (Pantothenic

Also known as: B6, B6 Vitamin, Pyridoxal, Pyridoxal Phosphate, Pyridoxal Phosphate (PLP), Vitamin B6 Pyridoxal Phosphate

Factor X Activity,

Vitamin B6

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The Mental Wellness Insight: Blood Biomarker Analysis panel contains 18 tests with 103 biomarkers.

The Mental Wellness Insight: Blood Biomarker Analysis panel is a comprehensive suite of blood tests designed specifically to uncover underlying biological factors that may contribute to mental health challenges such as anxiety, depression, and stress. By examining a range of biomarkers, from hormone levels to nutritional deficiencies, this panel provides valuable insights that can guide personalized treatment strategies for improved mental wellness. Here's how the panel is structured:

Thyroid Health

  • TSH (Thyroid Stimulating Hormone): Crucial for diagnosing thyroid disorders. An imbalance can cause symptoms similar to depression or anxiety.
  • Free T4: Measures the active thyroid hormone in your bloodstream. Abnormal levels can impact mood and energy.
  • Free T3: Another active thyroid hormone, critical for mood regulation and cognitive function. Imbalances can contribute to mental health issues.

Nutritional Status

  • Vitamin D Level Test: Investigates vitamin D levels, with deficiencies linked to mood disorders. Addressing low vitamin D can help improve mood and overall well-being.
  • Complete Blood Count (CBC): Offers an overview of general health and checks for anemia, which can contribute to fatigue and depressive symptoms.
  • Folate (Vitamin B9) Level: Identifies folate deficiencies, associated with depression. Supplementing folate can aid in mood stabilization.
  • Omega-3 and Omega-6 Fatty Acids Test: Measures these essential fats, vital for brain health. Balancing omega-3 and omega-6 levels can support mental health and cognitive function.
  • Magnesium Level Test: Assesses magnesium levels; low magnesium is linked to increased anxiety and depression. Correcting this deficiency may improve mental health symptoms.
  • B12 and Other B Vitamins Test: Evaluates levels of crucial B vitamins for brain health and energy. Addressing deficiencies can enhance mood and energy levels.
  • Amino Acids Test: Analyzes essential amino acids, the building blocks for neurotransmitters that regulate mood. Adjusting dietary intake based on these levels can help in managing mental health.

Hormonal Balance

  • Cortisol Test: Measures cortisol levels, providing insight into stress response and potential adrenal fatigue, which can impact mental health.
  • Sex Hormone Tests: Includes estrogen, progesterone, and testosterone levels. Hormonal imbalances can significantly affect mood and are important to consider in the context of mental health. The Sex Hormone Tests within the Mental Wellness Insight: Blood Biomarker Analysis panel are pivotal for understanding how hormonal imbalances might be influencing mental health. This group of tests includes measurements of estrogen, progesterone, and testosterone levels, each playing a unique role in mood regulation and overall mental well-being. Here's an expanded look at each hormone and its significance:
  • Estrogen
    • Role: Estrogen has a profound impact on the brain, influencing mood, attention, and cognitive functions. It's known to interact with neurotransmitters like serotonin and dopamine, which are directly linked to mood regulation.
    • Imbalances: Low levels of estrogen can lead to mood swings, depression, and anxiety, especially during the premenstrual phase, postpartum period, and menopause. Conversely, excessively high estrogen levels can also contribute to mood disturbances.
    • Benefits of Testing: Identifying estrogen imbalances can help tailor treatments such as hormone replacement therapy (HRT), lifestyle changes, or dietary adjustments to stabilize mood and improve mental health.
  • Progesterone
    • Role: Progesterone is known for its calming effects on the brain. It works by modulating GABA receptors, which help reduce stress and anxiety levels.
    • Imbalances: Low progesterone levels can contribute to anxiety, irritability, and mood swings. This imbalance is often observed in the latter half of the menstrual cycle and can exacerbate symptoms of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD).
    • Benefits of Testing: Measuring progesterone levels can guide the implementation of treatments to alleviate symptoms of anxiety and mood disorders, especially those that fluctuate with menstrual cycles.
  • Testosterone
    • Role: Testosterone influences energy levels, libido, and mood. Though often considered a male hormone, it plays a crucial role in women's health as well.
    • Imbalances: In men, low testosterone levels are linked to fatigue, depression, and irritability. In women, high testosterone levels can be associated with polycystic ovary syndrome (PCOS), leading to mood disturbances and anxiety.
    • Benefits of Testing: Understanding testosterone levels can assist in addressing mood disorders and mental fatigue by adjusting hormone levels through medication, lifestyle changes, or dietary modifications.

By analyzing the levels of these sex hormones, the Mental Wellness Insight: Blood Biomarker Analysis panel provides critical insights into the hormonal underpinnings of mood disorders and mental health challenges. Addressing these hormonal imbalances through targeted interventions can significantly improve an individual's quality of life, mood stability, and overall mental wellness

By grouping these tests into categories focused on thyroid health, nutritional status, hormonal balance, and other contributing factors, the Mental Wellness Insight: Blood Biomarker Analysis panel offers a holistic view of the physical influences on mental health. This panel empowers individuals and healthcare providers with the information needed to identify and address specific biological factors that may be contributing to mental health issues, paving the way for targeted interventions that can enhance mental wellness and quality of life.

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