Urinalysis, Complete and Uric Acid Most Popular

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Also known as: Serum Urate, UA

Uric Acid

Uric acid is a chemical created when the body breaks down substances called purines. Purines are found in some foods and drinks. These include liver, anchovies, mackerel, dried beans and peas, and beer. Most uric acid dissolves in blood and travels to the kidneys. From there, it passes out in urine. If your body produces too much uric acid or doesn't remove enough if it, you can get sick. A high level of uric acid in the blood is called hyperuricemia.

Also known as: UA, Complete, Urinalysis UA Complete, Urine Analysis, Complete

Amorphous Sediment

Appearance

Bacteria

Bacteria are living things that have only one cell. Most bacteria won't hurt you - less than 1 percent of the different types make people sick. Many are helpful. Some bacteria help to digest food, destroy disease-causing cells, and give the body needed vitamins. But infectious bacteria can make you ill. They reproduce quickly in your body. Many give off chemicals called toxins, which can damage tissue and make you sick. Examples of bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli.

Bilirubin

Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. A small amount of older red blood cells are replaced by new blood cells every day. Bilirubin is left after these older blood cells are removed. The liver helps break down bilirubin so that it can be removed from the body in the stool.

Calcium Oxalate Crystals

Calcium oxalate is a chemical compound that forms envelope-shaped crystals. A major constituent of human kidney stones.

Casts

Urinary casts are cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Color

Crystals

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

Glucose

A blood glucose test measures the amount of a sugar called glucose in a sample of your blood. Glucose is a major source of energy for most cells of the body, including those in the brain. The hormones insulin and glucagon help control blood glucose levels.

Granular Cast

The second-most common type of cast, granular casts can result either from the breakdown of cellular casts or the inclusion of aggregates of plasma proteins (e.g., albumin) or immunoglobulin light chains. Depending on the size of inclusions, they can be classified as fine or coarse, though the distinction has no diagnostic significance. Their appearance is generally more cigar-shaped and of a higher refractive index than hyaline casts. While most often indicative of chronic renal disease, these casts, as with hyaline casts, can also be seen for a short time following strenuous exercise

Hyaline Cast

Urinary casts are tiny tube-shaped particles. Urinary casts may be made up of white blood cells, red blood cells, kidney cells, or substances such as protein or fat. The most common type of cast, hyaline casts are solidified Tamm-Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and, as such, they may be seen in normal individuals in dehydration or vigorous exercise. Hyaline casts are cylindrical and clear, with a low refractive index,

Ketones

Ketones are substances produced in the liver when fat cells break down in the blood. A serum ketone test is a measurement of how many ketones are in the blood.

Leukocyte Esterase

Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.

Nitrite

Occult Blood

The test looks for hidden (occult) blood in a specimen sample. It can find blood even if you cannot see it yourself.

Ph

Level of acid

Protein

Body fluids contain many different proteins that serve diverse functions such as transport of nutrients, removal of toxins, control of metabolic processes, and defense against invaders. Protein electrophoresis is a method for separating these proteins based on their size and electrical charge. When body fluids are separated by electrophoresis, they form a characteristic pattern of bands of different widths and intensities, reflecting the mixture of proteins present. This pattern is divided into five fractions, called albumin, alpha 1, alpha 2, beta, and gamma. In some cases, the beta fraction is further divided into beta 1 and beta 2. Albumin, which is produced in the liver, accounts for about 60% of the protein in the blood. "Globulins" is a collective term used to refer to proteins other than albumin. With the exception of the immunoglobulins and some complement proteins, most of the globulins are also produced in the liver. Immunofixation electrophoresis (IFE) is a method used to identify abnormal bands seen on serum, urine, or CSF protein electrophoresis, as to which type of antibody (immunoglobulin) is present.

Rbc

RBCs contain hemoglobin, which carries oxygen. How much oxygen your body tissues get depends on how many RBCs you have and how well they work.

Reducing Substances

Renal Epithelial Cells

Specific Gravity

Squamous Epithelial Cells

Transitional Epithelial

Triple Phosphate Crystals

Struvite stones (triple phosphate/magnesium ammonium phosphate) - about 10–15% of urinary calculi are composed of struvite (ammonium magnesium phosphate, NH4MgPO4·6H2O).[44] Struvite stones (also known as "infection stones", urease or triple-phosphate stones), form most often in the presence of infection by urea-splitting bacteria

Uric Acid Crystals

Abnormal crystals may appear in urine as a result of pathology or due to normal catabolism

WBC

WBCs help fight infections. They are also called leukocytes. There are five major types of white blood cells: basophils, eosinophils, lymphocytes (T cells and B cells), monocytes and neutrophils

YEAST

Candida is the scientific name for yeast. It is a fungus that lives almost everywhere, including in your body. Usually, your immune system keeps yeast under control. If you are sick or taking antibiotics, it can multiply and cause an infection.
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The Urinalysis, Complete and Uric Acid panel contains 2 tests with 28 biomarkers.

Brief Description: The Urinalysis Complete and Uric Acid Panel is a diagnostic tool combining a comprehensive Urinalysis Complete with a Uric Acid test to assess kidney function, detect urinary tract disorders, and evaluate uric acid levels in the blood, which can contribute to conditions like gout and kidney stones.

NOTE: Only measurable biomarkers will be reported.

Collection Method: Blood Draw and Urine Collection

Specimen Type: Serum and Urine

Test Preparation: Specimen should be collected mid-stream to minimize contamination and improve accuracy.

When and Why the Panel May Be Ordered

This panel is often ordered for individuals presenting symptoms of urinary tract infections (UTIs), kidney disorders, or gout. It can also be part of routine health assessments, especially in patients with a history of kidney stones, gout, or those on treatments that may affect uric acid levels or kidney function.

What the Urinalysis Complete and Uric Acid Panel Checks For

  • Urinalysis Complete: This test evaluates various components of urine, including appearance, concentration, and content of substances like proteins, glucose, and blood. It can identify signs of infections, kidney disease, and other urinary tract issues.
  • Uric Acid: Measures the level of uric acid in the blood, a waste product formed from the breakdown of purines found in some foods and drinks. High levels can lead to gout and are associated with kidney stones and kidney disease.

Detected Conditions and Diseases

This panel is instrumental in diagnosing and monitoring:

  • Urinary Tract Infections (UTIs): Identified through abnormal findings in the urinalysis, such as the presence of leukocytes, nitrates, or bacteria.
  • Kidney Disorders: Indicated by abnormalities in urine composition, such as elevated protein levels or the presence of blood cells.
  • Gout: Characterized by elevated uric acid levels, leading to crystal formation in joints and acute pain.
  • Kidney Stones: High uric acid levels can contribute to the formation of kidney stones, with urinalysis identifying potential stone-forming elements.

Clinical Application of Panel Results

Healthcare professionals leverage the panel results to:

  • Diagnose and Treat UTIs and Kidney Disorders: Identifying infections and renal function abnormalities to guide treatment decisions.
  • Manage Gout: Monitoring uric acid levels to adjust dietary recommendations and medications to prevent gout flare-ups.
  • Prevent Kidney Stones: Assessing risk factors and implementing strategies to reduce stone formation.

The Urinalysis Complete and Uric Acid Panel provides a dual-function assessment critical for diagnosing and managing a range of urinary tract and metabolic conditions. By evaluating both urine composition and uric acid levels, healthcare providers can gain valuable insights into an individual's renal health and metabolic status, guiding effective treatment and preventive measures.

We advise having your results reviewed by a licensed medical healthcare professional for proper interpretation of your results.

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