The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.
Also known as: MMR IgG Panel Measles Mumps Rubella
Also known as: Chicken Pox, Herpes Zoster, Shingles, VaricellaZoster Virus Antibody IgG
The Vaccination Status Test Panel — Basic panel contains 5 tests with 9 biomarkers.
The Vaccination Status Test Panel — Basic panel is a comprehensive diagnostic tool designed to assess an individual's immunity to a range of infectious diseases, helping determine if a person has acquired immunity through previous vaccinations or past infections. This panel evaluates the presence of specific antibodies that protect against illnesses such as pertussis, diphtheria, tetanus, measles, mumps, rubella, polio, and varicella zoster (chickenpox). By examining the levels of these antibodies, healthcare providers can confirm immunity status or recommend necessary vaccinations, especially for individuals with incomplete vaccination records, travelers, or those at high risk of exposure.
The Vaccination Status Test Panel — Basic panel may be ordered for several reasons. A healthcare provider may recommend it if an individual is uncertain about their vaccination history, such as in cases where childhood vaccination records are missing. It is also useful for healthcare workers, travelers, or people in environments where there is a higher risk of exposure to vaccine-preventable diseases. For individuals with weakened immune systems or specific medical conditions, this panel can identify gaps in immunity that may put them at risk of severe complications from these diseases. Additionally, public health requirements may make the panel essential, such as verifying immunity before admission to school, university, or specific employment settings.
Each test in the Vaccination Status Test Panel — Basic panel is designed to detect antibodies against a specific pathogen or toxin that causes disease. The presence and concentration of these antibodies indicate whether a person has immunity to each illness.
The pertussis toxin IgG antibody test assesses immunity to pertussis, commonly known as whooping cough, which can be dangerous in infants and those with compromised respiratory systems. The test looks for IgG antibodies that are typically generated in response to vaccination or past infection with Bordetella pertussis, the bacteria responsible for pertussis. Detecting these antibodies can help confirm immunity, which is particularly important for healthcare workers, caregivers, and individuals in close contact with young children.
The diphtheria and tetanus antitoxoid antibody test measures the antibodies against the toxins produced by Corynebacterium diphtheriae and Clostridium tetani, the bacteria that cause diphtheria and tetanus. Diphtheria can lead to severe respiratory issues and even death, while tetanus causes muscle stiffness and spasms, often fatal if untreated. Vaccination with the DTaP or Tdap vaccines typically provides immunity to both diseases. This test can help determine if a person’s immunity to these toxins remains active or if a booster vaccination is needed.
The measles IgG antibody test checks for immunity against the measles virus, a highly contagious virus that can cause severe complications, including pneumonia and encephalitis. Immunity is usually achieved through the MMR vaccine (measles, mumps, rubella) or a past infection. Detecting IgG antibodies for measles indicates that a person has protective immunity, reducing the likelihood of contracting or spreading the virus.
The mumps IgG antibody test detects antibodies to the mumps virus, which causes swelling of the salivary glands and can lead to complications like meningitis, hearing loss, or infertility. Like measles, immunity to mumps is typically acquired through the MMR vaccine or previous exposure. This test verifies immunity, ensuring that an individual is less susceptible to contracting or transmitting mumps in high-risk areas.
The rubella IgG antibody test evaluates immunity to the rubella virus, also known as German measles. Although generally mild, rubella can cause severe congenital defects if contracted by pregnant women during the first trimester. The test checks for antibodies that are typically acquired via the MMR vaccine or past exposure, confirming immunity and helping prevent transmission to vulnerable populations, especially pregnant individuals.
The poliovirus antibody test looks for immunity to types 1 and 3 of the poliovirus, a virus known for causing poliomyelitis, which can lead to paralysis or even death. Polio immunity is achieved through the inactivated polio vaccine (IPV) or the oral polio vaccine (OPV), both of which prevent poliovirus infection. This test helps verify immunity status, ensuring the person is protected from these two poliovirus strains, particularly in areas where polio remains a concern.
The varicella zoster virus IgG antibody test detects immunity to varicella zoster, the virus that causes chickenpox and can later reactivate as shingles. Immunity to varicella zoster is usually conferred through vaccination or previous infection with chickenpox. This test confirms immunity, which is critical for healthcare workers, pregnant women, and immunocompromised individuals who are at increased risk for complications from the virus.
Healthcare providers use the results of the Vaccination Status Test Panel — Basic panel to assess the immune status of individuals and guide decisions on vaccination needs. If antibody levels indicate a lack of immunity to any of the diseases included in the panel, a healthcare provider may recommend vaccination or booster doses to ensure adequate protection. For individuals with sufficient antibody levels, no further vaccination may be necessary, potentially avoiding unnecessary medical costs and interventions. For those planning to travel or work in high-risk areas, confirming immunity status can help reduce the risk of exposure and transmission. Healthcare providers also use these results to counsel patients on preventive health practices and make informed recommendations on any additional necessary tests or health assessments.
The Vaccination Status Test Panel — Basic panel serves as a critical tool in preventive healthcare, offering individuals and healthcare providers valuable information about immunity status against several significant diseases. By identifying potential gaps in immunity, the panel enables healthcare providers to recommend necessary vaccinations, helping protect the individual and the broader community from outbreaks of vaccine-preventable diseases. Whether for personal peace of mind, professional requirements, or specific health needs, this panel is essential in modern healthcare, underscoring the importance of vaccination and immunity assessment in overall health management.