von Willebrand Factor Collagen Binding Assay

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The following is a list of what is included in the item above. Click the test(s) below to view what biomarkers are measured along with an explanation of what the biomarker is measuring.

Ratio (Cba/Vw Ag)

Vwf: Collagen Binding

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The von Willebrand Factor Collagen Binding Assay test contains 1 test with 2 biomarkers.

The Collagen Binding Assay (vWF:CBA) is a test procedure that quantifies the binding of vWF to collagen. Collagen binding of vWF is associated with the functionally more important HMW forms of vWF. Therefore, vWF:CBA may correlate more closely with vWF function and bleeding problems than vWF antigen assay (vWF: Ag) which measures total vWF multimers. When used in conjunction with the vWF: Ag assay, vWF:CBA can be used to differentiate between vWD type 1 and type 2 (A and B subtypes) by calculating a ratio of the two assay results (ratio = vWF:CBA/vWFAg).

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